onr:"swepub:oai:gup.ub.gu.se/270828"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03466naa a2200361 4500 | |
| 001 | oai:gup.ub.gu.se/270828 | |
| 003 | SwePub | |
| 008 | 240910s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2708282 URI |
| 024 | 7 | a https://doi.org/10.1007/s00464-017-5808-22 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Hedenström, Peru Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xhperi |
| 245 | 1 0 | a High clinical impact and diagnostic accuracy of EUS-guided biopsy sampling of subepithelial lesions: a prospective, comparative study. |
| 264 | c 2017-08-15 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2018 |
| 520 | a In a tertiary center setting we aimed to study the diagnostic accuracy and clinical impact of EUS-guided biopsy sampling (EUS-FNB) with a reverse bevel needle compared with that of fine needle aspiration (EUS-FNA) in the work-up of subepithelial lesions (SEL).All patients presenting with SELs referred for EUS-guided sampling were prospectively included in 2012-2015. After randomization of the first pass modality, dual sampling with both EUS-FNB and EUS-FNA was performed in each lesion. Outcome measures in an intention-to-diagnose analysis were the diagnostic accuracy, technical failures, and adverse events. The clinical impact was measured as the performance of additional diagnostic procedures post-EUS and the rate of unwarranted resections compared with a reference cohort of SELs sampled in the same institution 2006-2011.In 70 dual sampling procedures of unique lesions (size: 6-220mm) the diagnostic sensitivity for malignancy and the overall accuracy of EUS-FNB was superior to EUS-FNA compared head-to-head (90 vs 52%, and 83 vs 49%, both p<0.001). The adverse event rate of EUS-FNB was low (1.2%). EUS-FNB in 2012-2015 had a positive clinical impact in comparison with the reference cohort demonstrated by less cases referred for an additional diagnostic procedure, 12/83 (14%) vs 39/73 (53%), p<0.001, and fewer unwarranted resections in cases subjected to surgery, 3/48 (6%) vs 12/35 (34%), p=0.001.EUS-FNB with a reverse bevel needle is safe and superior to EUS-FNA in providing a conclusive diagnosis of subepithelial lesions. This biopsy sampling approach facilitates a rational clinical management and accurate treatment. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 700 | 1 | a Marschall, Hanns-Ulrich,d 19544 aut |
| 700 | 1 | a Nilsson, Bengt E,d 19494 aut |
| 700 | 1 | a Demif, Akir4 aut |
| 700 | 1 | a Lindkvist, Björn4 aut |
| 700 | 1 | a Nilsson, Ola,d 19574 aut |
| 700 | 1 | a Sadik, Riadh,d 19634 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition4 org |
| 773 | 0 | t Surgical endoscopyd : Springer Science and Business Media LLCg 32:3, s. 1304-1313q 32:3<1304-1313x 1432-2218x 0930-2794 |
| 856 | 4 | u https://link.springer.com/content/pdf/10.1007%2Fs00464-017-5808-2.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/270828 |
| 856 | 4 8 | u https://doi.org/10.1007/s00464-017-5808-2 |
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