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In vivo Detection o...
In vivo Detection of Alzheimer's Disease.
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- Leuzy, Antoine (författare)
- Karolinska Institute
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- Heurling, Kerstin (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Ashton, Nicholas J. (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Schöll, Michael, 1980 (författare)
- University of Gothenburg,Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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- Zimmer, Eduardo R (författare)
- Federal University of Rio Grande do Sul,Pontifical Catholic University of Rio Grande do Sul
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(creator_code:org_t)
- 2018
- 2018
- Engelska.
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Ingår i: The Yale journal of biology and medicine. - 1551-4056 .- 0044-0086. ; 91:3, s. 291-300
- Relaterad länk:
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https://www.ncbi.nlm... (free)
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Abstract
Ämnesord
Stäng
- Recent revisions to the diagnostic criteria for Alzheimer's disease (AD) incorporated conceptual advances in the field. Specifically, AD is now recognized to encompass a continuum, spanning from preclinical (accruing brain pathology in the absence of symptoms) through symptomatic predementia (prodromal AD, mild cognitive impairment) and dementia phases. The role of biological markers (biomarkers) of both the underlying molecular pathologies and related neurodegenerative changes has also been acknowledged. In this abridged review, we provide an overview of fluid (cerebrospinal fluid and blood) and molecular imaging-based biomarkers used within the field and discuss the potential role of computer driven artificial intelligence approaches for both the early and accurate identification of AD and as a tool for population enrichment in clinical trials testing candidate disease modifying therapies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Alzheimer Disease
- diagnosis
- Amyloid beta-Peptides
- metabolism
- Animals
- Biomarkers
- metabolism
- Diagnostic Imaging
- Humans
- Alzheimer’s disease
- Diagnosis
- Fluid biomarkers
- Medical imaging
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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