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Total versus subtot...
Total versus subtotal parathyroidectomy for secondary hyperparathyroidism
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- Isaksson, Elin (författare)
- Lund University,Lunds universitet,Endokrin- och sarkomkirurgi,Forskargrupper vid Lunds universitet,Endocrine and Sarcoma Surgery,Lund University Research Groups
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- Ivarsson, Kerstin (författare)
- Lund University,Lunds universitet,Kliniska studier vid kronisk njursjukdom (CKD),Forskargrupper vid Lunds universitet,Clinical studies in CKD,Lund University Research Groups
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- Akaberi, Shahriar (författare)
- Lund University,Lunds universitet,Kliniska studier vid kronisk njursjukdom (CKD),Forskargrupper vid Lunds universitet,Clinical studies in CKD,Lund University Research Groups
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- Muth, Andreas, 1974 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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- Prutz, K. G. (författare)
- Helsingborg Hospital
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- Clyne, Naomi (författare)
- Lund University,Lunds universitet,Kliniska studier vid kronisk njursjukdom (CKD),Forskargrupper vid Lunds universitet,Clinical studies in CKD,Lund University Research Groups
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- Sterner, Gunnar (författare)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Almquist, Martin (författare)
- Lund University,Lunds universitet,Endokrin- och sarkomkirurgi,Forskargrupper vid Lunds universitet,Endocrine and Sarcoma Surgery,Lund University Research Groups
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(creator_code:org_t)
- Elsevier BV, 2019
- 2019
- Engelska.
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Ingår i: Surgery. - : Elsevier BV. - 0039-6060. ; 165:1, s. 142-150
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Background: It remains unclear whether total or subtotal parathyroidectomy for secondary hyperparathyroidism yields the best outcomes. We investigated mortality, cardiovascular events, hip fracture, and recurrent parathyroidectomy after total versus subtotal parathyroidectomy in patients on renal replacement therapy. Methods: Using the Swedish Renal Registry, the surgical registry for thyroid and parathyroid surgery, and the National Inpatient Registry, we identified patients who underwent parathyroidectomy between 1991 and 2013. We calculated the risk of outcome after total versus subtotal parathyroidectomy using COX's regression, adjusting for age, sex, cause of renal disease, time with a functioning graft before and after parathyroidectomy, Charlson comorbidity index, year of surgery, prevalent cardiovascular disease, time on dialysis, renal transplantation at parathyroidectomy, and treatment with calcimimetics before parathyroidectomy. Results: There were 824 patients who underwent parathyroidectomy, 388 total and 436 subtotal. There was no difference in mortality or risk of incident hip fracture between groups. Comparing the subtotal with the total parathyroidectomy, the adjusted hazard ratio (95% confidence interval) for cardiovascular events was 0.43 (0.25-0.72) and for recurrent parathyroidectomy 3.33 (1.33-8.32). Conclusion: There was a higher risk of cardiovascular events in patients after total parathyroidectomy compared with subtotal parathyroidectomy, but a lower risk of recurrent parathyroidectomy. (C) 2018 Elsevier Inc. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- long-term survival
- mineral metabolism
- dialysis patients
- patient
- survival
- morbidity
- risk
- association
- mortality
- fracture
- outcomes
- Surgery
- arlson me
- 1987
- journal of chronic diseases
- v40
- p373
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Surgery
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