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Erythropoiesis in m...
Erythropoiesis in multiply injured patients.
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- Robinson, Yohan, 1977 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics,Charité – Campus Benjamin Franklin, Klinik für Unfall- und Wiederherstellungschirurgie, Berlin
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Hostmann, Arwed (författare)
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Matenov, Alexander (författare)
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Ertel, Wolfgang (författare)
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Oberholzer, Andreas (författare)
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(creator_code:org_t)
- Ovid Technologies (Wolters Kluwer Health), 2006
- 2006
- Engelska.
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Ingår i: The Journal of trauma. - : Ovid Technologies (Wolters Kluwer Health). - 0022-5282 .- 1529-8809. ; 61:5, s. 1285-91
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Posttraumatic anemia in multiply injured patients is caused by hemorrhage, reduced red blood cell survival, and impaired erythropoiesis. Trauma-induced hyperinflammation causes impaired bone-marrow function by means of blunted erythropoietin (EPO) response, reduced iron availability, suppression and egress of erythroid progenitor cells. To treat posttraumatic anemia in severely injured patients, symptomatic therapy by blood transfusion is not sufficient. Furthermore, EPO, iron, and the use of red cell substitutes should be considered. The posttraumatic systemic inflammatory response syndrome (SIRS) induces posttraumatic anemia. Thus, a worsening of SIRS by a "second-hit" through blood transfusion ought to be avoided.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- Anemia
- etiology
- Erythrocyte Transfusion
- Erythrocytes
- pathology
- Erythropoiesis
- physiology
- Fluid Therapy
- Hemorrhage
- complications
- Humans
- Iron
- deficiency
- physiology
- Multiple Trauma
- physiopathology
- Resuscitation
- methods
- Systemic Inflammatory Response Syndrome
- physiopathology
- trauma
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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