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The use of allograf...
The use of allograft tendons in primary ACL reconstruction
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Hulet, C. (författare)
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Sonnery-Cottet, B. (författare)
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Stevenson, C. (författare)
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- Samuelsson, Kristian, 1977 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics
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Laver, L. (författare)
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Zdanowicz, U. (författare)
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Stufkens, S. (författare)
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Curado, J. (författare)
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Verdonk, P. (författare)
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Spalding, T. (författare)
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(creator_code:org_t)
- 2019-03-04
- 2019
- Engelska.
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Ingår i: Knee Surgery Sports Traumatology Arthroscopy. - : Springer Science and Business Media LLC. - 0942-2056 .- 1433-7347. ; 27:6, s. 1754-1770
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Purpose Graft choice in primary anterior cruciate ligament (ACL) reconstruction remains controversial. The use of allograft has risen exponentially in recent years with the attraction of absent donor site morbidity, reduced surgical time and reliable graft size. However, the published evidence examining their clinical effectiveness over autograft tendons has been unclear. The aim of this paper is to provide a current review of the clinical evidence available to help guide surgeons through the decision-making process for the use of allografts in primary ACL reconstruction. Methods The literature in relation to allograft healing, storage, sterilisation, differences in surgical technique and rehabilitation have been reviewed in addition to recent comparative studies and all clinical systematic reviews and meta-analyses. Results Early reviews have indicated a higher risk of failure with allografts due to association with irradiation for sterilisation and where rehabilitation programs and post-operative loading may ignore the slower incorporation of allografts. More recent analysis indicates a similar low failure rate for allograft and autograft methods of reconstruction when using non-irradiated allografts that have not undergone chemically processing and where rehabilitation has been slower. However, inferior outcomes with allografts have been reported in young (<25years) highly active patients, and also when irradiated or chemically processed grafts are used. Conclusion When considering use of allografts in primary ACL reconstruction, use of irradiation, chemical processing and rehabilitation programs suited to autograft are important negative factors. Allografts, when used for primary ACL reconstruction, should be fresh frozen and non-irradiated. Quantification of the risk of use of allograft in the young requires further evaluation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Nyckelord
- Anterior cruciate ligament reconstruction
- Allografts
- ACL
- Graft choice
- Decision making
- Autografts
- anterior cruciate ligament
- fresh-frozen allograft
- soft-tissue
- allograft
- patellar tendon
- failure rate
- biomechanical properties
- irradiated allograft
- hamstring autograft
- achilles allograft
- gamma-irradiation
- Orthopedics
- Sport Sciences
- Surgery
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Hulet, C.
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Sonnery-Cottet, ...
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Stevenson, C.
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Samuelsson, Kris ...
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Laver, L.
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Zdanowicz, U.
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visa fler...
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Stufkens, S.
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Curado, J.
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Verdonk, P.
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Spalding, T.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Ortopedi
- Artiklar i publikationen
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Knee Surgery Spo ...
- Av lärosätet
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Göteborgs universitet