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Sökning: onr:"swepub:oai:gup.ub.gu.se/287152" > Cohort profile: Thr...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004553naa a2200757 4500
001oai:gup.ub.gu.se/287152
003SwePub
008240528s2018 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/2871522 URI
0247 a https://doi.org/10.1136/bmjopen-2018-0232652 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Scheitz, Jan F4 aut
2451 0a Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration.
264 c 2018-09-17
264 1b BMJ,c 2018
520 a The ThRombolysis in Ischemic Stroke Patients (TRISP) collaboration aims to address clinically relevant questions about safety and outcomes of intravenous thrombolysis (IVT) and endovascular thrombectomy. The findings can provide observational information on treatment of patients derived from everyday clinical practice.TRISP is an open, investigator-driven collaborative research initiative of European stroke centres with expertise in treatment with revascularisation therapies and maintenance of hospital-based registries. All participating centres made a commitment to prospectively collect data on consecutive patients with stroke treated with IVT using standardised definitions of variables and outcomes, to assure accuracy and completeness of the data and to adapt their local databases to answer novel research questions.Currently, TRISP comprises 18 centres and registers >10000IVT-treated patients. Prior TRISP projects provided evidence on the safety and functional outcome in relevant subgroups of patients who were excluded, under-represented or not specifically addressed in randomised controlled trials (ie, pre-existing disability, cervical artery dissections, stroke mimics, prior statin use), demonstrated deficits in organisation of acute stroke care (ie, IVT during non-working hours, effects of onset-to-door time on onset-to-needle time), evaluated the association between laboratory findings on outcome after IVT and served to develop risk estimation tools for prediction of haemorrhagic complications and functional outcome after IVT.Further TRISP projects to increase knowledge of the effect and safety of revascularisation therapies in acute stroke are ongoing. TRISP welcomes participation and project proposals of further centres fulfilling the outlined requirements. In the future, TRISP will be extended to include patients undergoing endovascular thrombectomy.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a Administration
653 a Intravenous
653 a Brain Ischemia
653 a complications
653 a therapy
653 a Endovascular Procedures
653 a adverse effects
653 a Fibrinolytic Agents
653 a adverse effects
653 a therapeutic use
653 a Humans
653 a Intersectoral Collaboration
653 a Prospective Studies
653 a Registries
653 a Stroke
653 a etiology
653 a therapy
653 a Thrombectomy
653 a adverse effects
7001 a Gensicke, Henrik4 aut
7001 a Zinkstok, Sanne M4 aut
7001 a Curtze, Sami4 aut
7001 a Arnold, Marcel4 aut
7001 a Hametner, Christian4 aut
7001 a Pezzini, Alessandro4 aut
7001 a Turc, Guillaume4 aut
7001 a Zini, Andrea4 aut
7001 a Padjen, Visnja4 aut
7001 a Wegener, Susanne4 aut
7001 a Nordanstig, Annika4 aut
7001 a Kellert, Lars4 aut
7001 a Kägi, Georg4 aut
7001 a Bejot, Yannick4 aut
7001 a Michel, Patrik4 aut
7001 a Leys, Didier4 aut
7001 a Nolte, Christian H4 aut
7001 a Nederkoorn, Paul J4 aut
7001 a Engelter, Stefan T4 aut
7001 a Jood, Katarina,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xjooka
7102 a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org
7730 t BMJ opend : BMJg 8:9q 8:9x 2044-6055
8564 u https://bmjopen.bmj.com/content/bmjopen/8/9/e023265.full.pdf
8564 8u https://gup.ub.gu.se/publication/287152
8564 8u https://doi.org/10.1136/bmjopen-2018-023265

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