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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 10183naa a2202473 4500 | |
| 001 | oai:gup.ub.gu.se/291981 | |
| 003 | SwePub | |
| 008 | 240528s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2919812 URI |
| 024 | 7 | a https://doi.org/10.1074/mcp.RA119.0016772 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a De Leoz, M. L. A.4 aut |
| 245 | 1 0 | a NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods |
| 264 | 1 | c 2020 |
| 520 | a A broad-based interlaboratory study of glycosylation profiles of a reference and modified IgG antibody involving 103 reports from 76 laboratories. Glycosylation is a topic of intense current interest in the development of biopharmaceuticals because it is related to drug safety and efficacy. This work describes results of an interlaboratory study on the glycosylation of the Primary Sample (PS) of NISTmAb, a monoclonal antibody reference material. Seventy-six laboratories from industry, university, research, government, and hospital sectors in Europe, North America, Asia, and Australia submitted a total of 103 reports on glycan distributions. The principal objective of this study was to report and compare results for the full range of analytical methods presently used in the glycosylation analysis of mAbs. Therefore, participation was unrestricted, with laboratories choosing their own measurement techniques. Protein glycosylation was determined in various ways, including at the level of intact mAb, protein fragments, glycopeptides, or released glycans, using a wide variety of methods for derivatization, separation, identification, and quantification. Consequently, the diversity of results was enormous, with the number of glycan compositions identified by each laboratory ranging from 4 to 48. In total, one hundred sixteen glycan compositions were reported, of which 57 compositions could be assigned consensus abundance values. These consensus medians provide community-derived values for NISTmAb PS. Agreement with the consensus medians did not depend on the specific method or laboratory type. The study provides a view of the current state-of-the-art for biologic glycosylation measurement and suggests a clear need for harmonization of glycosylation analysis methods. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
| 653 | a Glycomics | |
| 653 | a mass spectrometry | |
| 653 | a fluorescence | |
| 653 | a glycosylation | |
| 653 | a glycoproteins | |
| 653 | a glycan | |
| 653 | a glycopeptide | |
| 653 | a interlaboratory study | |
| 653 | a NISTmAb | |
| 653 | a reference antibody | |
| 653 | a mass-spectrometry | |
| 653 | a lc-ms/ms | |
| 653 | a therapeutic antibodies | |
| 653 | a glycomic analysis | |
| 653 | a protein | |
| 653 | a quantification | |
| 653 | a identification | |
| 653 | a glycoproteins | |
| 653 | a quantitation | |
| 653 | a profiles | |
| 653 | a Biochemistry & Molecular Biology | |
| 700 | 1 | a Duewer, D. L.4 aut |
| 700 | 1 | a Fung, A.4 aut |
| 700 | 1 | a Liu, L.4 aut |
| 700 | 1 | a Yau, H. K.4 aut |
| 700 | 1 | a Potter, O.4 aut |
| 700 | 1 | a Staples, G. O.4 aut |
| 700 | 1 | a Furuki, K.4 aut |
| 700 | 1 | a Frenkel, R.4 aut |
| 700 | 1 | a Hu, Y. L.4 aut |
| 700 | 1 | a Sosic, Z.4 aut |
| 700 | 1 | a Zhang, P. Q.4 aut |
| 700 | 1 | a Altmann, F.4 aut |
| 700 | 1 | a Grunwald-Grube, C.4 aut |
| 700 | 1 | a Shao, C.4 aut |
| 700 | 1 | a Zaia, J.4 aut |
| 700 | 1 | a Evers, W.4 aut |
| 700 | 1 | a Pengelley, S.4 aut |
| 700 | 1 | a Suckau, D.4 aut |
| 700 | 1 | a Wiechmann, A.4 aut |
| 700 | 1 | a Resemann, A.4 aut |
| 700 | 1 | a Jabs, W.4 aut |
| 700 | 1 | a Beck, A.4 aut |
| 700 | 1 | a Froehlich, J. W.4 aut |
| 700 | 1 | a Huang, C. C.4 aut |
| 700 | 1 | a Li, Y.4 aut |
| 700 | 1 | a Liu, Y. M.4 aut |
| 700 | 1 | a Sun, S. W.4 aut |
| 700 | 1 | a Wang, Y. J.4 aut |
| 700 | 1 | a Seo, Y.4 aut |
| 700 | 1 | a An, H. J.4 aut |
| 700 | 1 | a Reichardt, N. C.4 aut |
| 700 | 1 | a Ruiz, J. E.4 aut |
| 700 | 1 | a Archer-Hartmann, S.4 aut |
| 700 | 1 | a Azadi, P.4 aut |
| 700 | 1 | a Bell, L.4 aut |
| 700 | 1 | a Lakos, Z.4 aut |
| 700 | 1 | a An, Y. M.4 aut |
| 700 | 1 | a Cipollo, J. F.4 aut |
| 700 | 1 | a Pucic-Bakovic, M.4 aut |
| 700 | 1 | a Stambuk, J.4 aut |
| 700 | 1 | a Lauc, G.4 aut |
| 700 | 1 | a Li, X.4 aut |
| 700 | 1 | a Wang, P. G.4 aut |
| 700 | 1 | a Bock, A.4 aut |
| 700 | 1 | a Hennig, R.4 aut |
| 700 | 1 | a Rapp, E.4 aut |
| 700 | 1 | a Creskey, M.4 aut |
| 700 | 1 | a Cyr, T. D.4 aut |
| 700 | 1 | a Nakano, M.4 aut |
| 700 | 1 | a Sugiyama, T.4 aut |
| 700 | 1 | a Leung, P. K. A.4 aut |
| 700 | 1 | a Link-Lenczowski, P.4 aut |
| 700 | 1 | a Jaworek, J.4 aut |
| 700 | 1 | a Yang, S.4 aut |
| 700 | 1 | a Zhang, H.4 aut |
| 700 | 1 | a Kelly, T.4 aut |
| 700 | 1 | a Klapoetke, S.4 aut |
| 700 | 1 | a Cao, R.4 aut |
| 700 | 1 | a Kim, J. Y.4 aut |
| 700 | 1 | a Lee, H. K.4 aut |
| 700 | 1 | a Lee, J. Y.4 aut |
| 700 | 1 | a Yoo, J. S.4 aut |
| 700 | 1 | a Kim, S. R.4 aut |
| 700 | 1 | a Suh, S. K.4 aut |
| 700 | 1 | a de Haan, N.4 aut |
| 700 | 1 | a Falck, D.4 aut |
| 700 | 1 | a Lageveen-Kammeijer, G. S. M.4 aut |
| 700 | 1 | a Wuhrer, M.4 aut |
| 700 | 1 | a Emery, R. J.4 aut |
| 700 | 1 | a Kozak, R. P.4 aut |
| 700 | 1 | a Liew, L. P.4 aut |
| 700 | 1 | a Royle, L.4 aut |
| 700 | 1 | a Urbanowicz, P. A.4 aut |
| 700 | 1 | a Packer, N. H.4 aut |
| 700 | 1 | a Song, X. M.4 aut |
| 700 | 1 | a Everest-Dass, A.4 aut |
| 700 | 1 | a Lattova, E.4 aut |
| 700 | 1 | a Cajic, S.4 aut |
| 700 | 1 | a Alagesan, K.4 aut |
| 700 | 1 | a Kolarich, D.4 aut |
| 700 | 1 | a Kasali, T.4 aut |
| 700 | 1 | a Lindo, V.4 aut |
| 700 | 1 | a Chen, Y.4 aut |
| 700 | 1 | a Goswami, K.4 aut |
| 700 | 1 | a Gau, B.4 aut |
| 700 | 1 | a Amunugama, R.4 aut |
| 700 | 1 | a Jones, R.4 aut |
| 700 | 1 | a Stroop, C. J. M.4 aut |
| 700 | 1 | a Kato, K.4 aut |
| 700 | 1 | a Yagi, H.4 aut |
| 700 | 1 | a Kondo, S.4 aut |
| 700 | 1 | a Yuen, C. T.4 aut |
| 700 | 1 | a Harazono, A.4 aut |
| 700 | 1 | a Shi, X. F.4 aut |
| 700 | 1 | a Magnelli, P. E.4 aut |
| 700 | 1 | a Kasper, B. T.4 aut |
| 700 | 1 | a Mahal, L.4 aut |
| 700 | 1 | a Harvey, D. J.4 aut |
| 700 | 1 | a O'Flaherty, R.4 aut |
| 700 | 1 | a Rudd, P. M.4 aut |
| 700 | 1 | a Saldova, R.4 aut |
| 700 | 1 | a Hecht, E. S.4 aut |
| 700 | 1 | a Muddiman, D. C.4 aut |
| 700 | 1 | a Kang, J. C.4 aut |
| 700 | 1 | a Bhoskar, P.4 aut |
| 700 | 1 | a Menard, D.4 aut |
| 700 | 1 | a Saati, A.4 aut |
| 700 | 1 | a Merle, C.4 aut |
| 700 | 1 | a Mast, S.4 aut |
| 700 | 1 | a Tep, S.4 aut |
| 700 | 1 | a Truong, J.4 aut |
| 700 | 1 | a Nishikaze, T.4 aut |
| 700 | 1 | a Sekiya, S.4 aut |
| 700 | 1 | a Shafer, A.4 aut |
| 700 | 1 | a Funaoka, S.4 aut |
| 700 | 1 | a Toyoda, M.4 aut |
| 700 | 1 | a de Vreugd, P.4 aut |
| 700 | 1 | a Caron, C.4 aut |
| 700 | 1 | a Pradhan, P.4 aut |
| 700 | 1 | a Tan, N. C.4 aut |
| 700 | 1 | a Mechref, Y.4 aut |
| 700 | 1 | a Patil, S.4 aut |
| 700 | 1 | a Rohrer, J. S.4 aut |
| 700 | 1 | a Chakrabarti, R.4 aut |
| 700 | 1 | a Dadke, D.4 aut |
| 700 | 1 | a Lahori, M.4 aut |
| 700 | 1 | a Zou, C. X.4 aut |
| 700 | 1 | a Cairo, C.4 aut |
| 700 | 1 | a Reiz, B.4 aut |
| 700 | 1 | a Whittal, R. M.4 aut |
| 700 | 1 | a Lebrilla, C. B.4 aut |
| 700 | 1 | a Wu, L. R.4 aut |
| 700 | 1 | a Guttman, A.4 aut |
| 700 | 1 | a Szigeti, M.4 aut |
| 700 | 1 | a Kremkow, B. G.4 aut |
| 700 | 1 | a Lee, K. H.4 aut |
| 700 | 1 | a Sihlbom, C.4 aut |
| 700 | 1 | a Adamczyk, Barbara,d 19854 aut |
| 700 | 1 | a Jin, Chunshengu Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology4 aut0 (Swepub:gu)xjinch |
| 700 | 1 | a Karlsson, Niclas G.,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology4 aut0 (Swepub:gu)xkanic |
| 700 | 1 | a Örnros, Jessicau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology4 aut |
| 700 | 1 | a Larson, Göran,d 1953u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för laboratoriemedicin,Department of Laboratory Medicine4 aut0 (Swepub:gu)xlarsg |
| 700 | 1 | a Nilsson, Jonas,d 1970u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för laboratoriemedicin,Department of Laboratory Medicine4 aut0 (Swepub:gu)xnjoni |
| 700 | 1 | a Meyer, B.4 aut |
| 700 | 1 | a Wiegandt, A.4 aut |
| 700 | 1 | a Komatsu, E.4 aut |
| 700 | 1 | a Perreault, H.4 aut |
| 700 | 1 | a Bodnar, E. D.4 aut |
| 700 | 1 | a Said, N.4 aut |
| 700 | 1 | a Francois, Y. N.4 aut |
| 700 | 1 | a Leize-Wagner, E.4 aut |
| 700 | 1 | a Maier, S.4 aut |
| 700 | 1 | a Zeck, A.4 aut |
| 700 | 1 | a Heck, A. J. R.4 aut |
| 700 | 1 | a Yang, Y.4 aut |
| 700 | 1 | a Haselberg, R.4 aut |
| 700 | 1 | a Yu, Y. Q.4 aut |
| 700 | 1 | a Alley, W.4 aut |
| 700 | 1 | a Leone, J. W.4 aut |
| 700 | 1 | a Yuan, H.4 aut |
| 700 | 1 | a Stein, S. E.4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi4 org |
| 773 | 0 | t Molecular & Cellular Proteomicsg 19:1, s. 11-30q 19:1<11-30x 1535-9476 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/291981 |
| 856 | 4 8 | u https://doi.org/10.1074/mcp.RA119.001677 |
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- Everest-Dass, A.
- Lattova, E.
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- Alagesan, K.
- Kolarich, D.
- Kasali, T.
- Lindo, V.
- Chen, Y.
- Goswami, K.
- Gau, B.
- Amunugama, R.
- Jones, R.
- Stroop, C. J. M.
- Kato, K.
- Yagi, H.
- Kondo, S.
- Yuen, C. T.
- Harazono, A.
- Shi, X. F.
- Magnelli, P. E.
- Kasper, B. T.
- Mahal, L.
- Harvey, D. J.
- O'Flaherty, R.
- Rudd, P. M.
- Saldova, R.
- Hecht, E. S.
- Muddiman, D. C.
- Kang, J. C.
- Bhoskar, P.
- Menard, D.
- Saati, A.
- Merle, C.
- Mast, S.
- Tep, S.
- Truong, J.
- Nishikaze, T.
- Sekiya, S.
- Shafer, A.
- Funaoka, S.
- Toyoda, M.
- de Vreugd, P.
- Caron, C.
- Pradhan, P.
- Tan, N. C.
- Mechref, Y.
- Patil, S.
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- Chakrabarti, R.
- Dadke, D.
- Lahori, M.
- Zou, C. X.
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- Reiz, B.
- Whittal, R. M.
- Lebrilla, C. B.
- Wu, L. R.
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