Automated Quantification of Diseased Thoracic Aortic Longitudinal Centerline and Surface Curvatures

Bondesson, Johan,1991Chalmers tekniska högskola,Chalmers University of Technology (författare)

Precise description of vascular morphometry is crucial to support medical device manufacturers and clinicians for improving device development and interventional outcomes. A compact and intuitive method is presented to automatically characterize the surface geometry of tubular anatomic structures and quantify surface curvatures starting from generic stereolithographic (STL) surfaces. The method was validated with software phantoms and used to quantify the longitudinal surface curvatures of 37 human thoracic aortas with aneurysm or dissection. The quantification of surface curvatures showed good agreement with analytic solutions from the software phantoms, and demonstrated better agreement as compared to estimation methods using only centerline geometry and cross-sectional radii. For the human thoracic aortas, longitudinal inner surface curvature was significantly higher than centerline curvature (0.33 +/- 0.06 versus 0.16 +/- 0.02cm(-1) for mean; 1.38 +/- 0.48 versus 0.45 +/- 0.11cm(-1) for peak; both p<0.001). These findings show the importance of quantifying surface curvatures in order to better describe the geometry and biomechanical behavior of the thoracic aorta, which can assist in treatment planning and supplying device manufactures with more precise boundary conditions for mechanical evaluation.

Suh, G. Y.Stanford University (författare)
Lundh, Torbjörn,1965Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper,Department of Mathematical Sciences,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)torbjrn (författare)
Lee, J. T.Stanford University (författare)
Dake, M. D.Stanford University (författare)
Cheng, C. P.Stanford University (författare)
Chalmers tekniska högskolaStanford University (creator_code:org_t)

Ingår i:Journal of Biomechanical Engineering-Transactions of the Asme: ASME International142:40148-07311528-8951
Ingår i:Journal of Biomechanical Engineering: ASME International142:41528-8951

Av författaren/redakt...: Bondesson, Johan ...; Suh, G. Y.; Lundh, Torbjörn, ...; Lee, J. T.; Dake, M. D.; Cheng, C. P.

Om ämnet

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Medicinteknik; och Annan medicintek ...

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Materialteknik; och Annan materialte ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.