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Quality of life in ...
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Fabrazzo, M.
(författare)
Quality of life in Klinefelter patients on testosterone replacement therapy compared to healthy controls: an observational study on the impact of psychological distress, personality traits, and coping strategies
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
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2020-08-31
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Springer Science and Business Media LLC,2021
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LIBRIS-ID:oai:gup.ub.gu.se/296633
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https://gup.ub.gu.se/publication/296633URI
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https://doi.org/10.1007/s40618-020-01400-8DOI
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Purpose We aimed to verify if 1 year-testosterone-replacement therapy could produce a psychopathological recovery and a satisfactory quality of life in Klinefelter syndrome (KS) patients compared to matched healthy controls. Further, we analyzed personality traits and coping strategies, an issue not yet examined in androgen-treated KS patients. We also enquired whether any of the sociodemographic and psychological variables might predict a patient's general and sexual life satisfaction. Methods The Quality of Life Enjoyment and Satisfaction Questionnaire and the Temperament and Character Inventory-Revised were administered to both 23 KS patients and matched healthy subjects. Psychopathology was investigated by the Symptom Checklist-90-Revised (SCL-90-R) and the Mini-mental State Examination. The COPE Inventory was used to identify cognitive and behavioral strategies to manage disease-related distress. Results In testosterone-treated KS patients, when compared with controls, SCL-90-R subscales analysis evidenced high psychological distress, mainly presented as obsessive thoughts, hanger-hostility, phobias, and psychoticism. Self-directedness and self-transcendence, along with the prevalent use ofemotion-focusedcoping strategies, outlined the personality of our KS patients. Depression and somatization proved to be predictors of general life dissatisfaction. Depression, anger-hostility, and paranoid ideation, instead, emerged as predictors of sexual life dissatisfaction. Conclusion Endocrinologists should cooperate with mental health providers to foster a better outcome of the disease in KS patients.
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Accardo, G.
(författare)
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Abbondandolo, I.
(författare)
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Goglia, G.
(författare)
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Esposito, DanielaGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xespda
(författare)
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Sampogna, G.
(författare)
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Catapano, F.
(författare)
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Giugliano, D.
(författare)
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Pasquali, D.
(författare)
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Göteborgs universitetInstitutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Endocrinological Investigation: Springer Science and Business Media LLC44:5, s. 1053-10630391-40971720-8386
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