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Wide temporal horns...
Wide temporal horns are associated with cognitive dysfunction, as well as impaired gait and incontinence
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- Lilja-Lund, Otto (författare)
- Umeå universitet,Neurovetenskaper,Umeå Univ, Dept Clin Sci, Östersunds Sjukhus, Neurosci, S-83183 Östersund, Sweden
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- Kockum, Karin (författare)
- Umeå universitet,Neurovetenskaper,Umeå Univ, Dept Clin Sci, Östersunds Sjukhus, Neurosci, S-83183 Östersund, Sweden
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- Hellström, Per (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Univ Gothenburg, Inst Neurosci & Physiol, Gothenburg, Sweden
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- Soderstrom, L. (författare)
- Östersund Hosp, Unit Res Educ & Dev, Östersund, Region Jämtland, Sweden
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- Nyberg, Lars, 1966- (författare)
- Umeå universitet,Diagnostisk radiologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden
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- Laurell, Katarina, 1967- (författare)
- Uppsala universitet,Landtblom: Neurovetenskap
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(creator_code:org_t)
- 2020-10-23
- 2020
- Engelska.
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1
- Relaterad länk:
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https://www.nature.c...
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The association between morphology of the brain and symptoms of suspected idiopathic normal pressure hydrocephalus (iNPH) is largely unknown. We investigated how ventricular expansion (width of the temporal horns [TH], callosal angle [CA], and Evans' index [EI]) related to symptom severity in suspected iNPH. Participants (n=168; 74.9 years +/- SD 6.7; 55% females) from the general population underwent neurological examination, computed tomography, and neuropsychological testing. Multiple linear regression analysis revealed that wide TH was independently associated with all examined iNPH symptoms (p<0.01) except for fine-motor performance, whereas a narrow CA only was associated to specific motor and cognitive functions (p<0.05). TH and EI correlated significantly with incontinence (r(s) 0.17 and r(s) 0.16; p<0.05). In conclusion, wide TH was significantly associated with most iNPH-symptoms. This finding potentially reflects the complex nature of the hippocampus, however further studies are needed to demonstrate functional connectivity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- normal-pressure hydrocephalus
- shunt surgery
- radial width
- hippocampal-formation
- corpus-callosum
- variability
- ventricle
- scale
- mri
- Science & Technology - Other Topics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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