Sökning: onr:"swepub:oai:gup.ub.gu.se/300258" >
Parallel gradients ...
Parallel gradients in F-ENO and in the prevalences of asthma and atopy in adult general populations of Sweden, Finland and Estonia - A Nordic EpiLung study
-
- Lassmann-Klee, P. G. (författare)
- Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Finland
-
Piirilla, P. L. (författare)
-
- Brumpton, B. (författare)
- Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
-
visa fler...
-
- Larsson, Matz, 1955- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Health Promotion Centre, University of Lund, And Örebro University Hospital, Örebro, Sweden
-
- Sundblad, B. M. (författare)
- Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden,National Institute for Health Development, Tallinn, Estonia; The North Estonia Medical Centre, Tallinn, Estonia
-
- Polluste, J. (författare)
- National Institute for Health Development, Tallinn, Estonia
-
- Juusela, M. (författare)
- The Finnish Institute of Lung Health, FILHA, Helsinki, Finland
-
- Routious, A. (författare)
- Department of Pulmonary Medicine, Heart and Lung Center, Helsinki University Central Hospital and University of Helsinki, Finland,Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Finland
-
Mere, M. (författare)
-
- Lindqvist, A. (författare)
- Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Finland
-
- Kankaanranta, Hannu, 1967 (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre,Institutionen för medicin,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Department of Respiratory Medicine, Sein ̈ajoki Central Hospital, Sein ̈ajoki, Finland; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden,Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
-
- Backman, Helena (författare)
- Luleå tekniska universitet,Umeå universitet,Avdelningen för hållbar hälsa,Department of Health Sciences, Luleå University of Technology, Luleå, Sweden,Omvårdnad och medicinsk teknik,Department of Public Health and Clinical Medicine, Division of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
-
- Langhammer, A. (författare)
- HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway and Central Norway Regional Health Authority, Trondheim, Norway
-
- Rönmark, Eva (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Division of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
-
- Lundbäck, Bo, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre,Institutionen för medicin,Institute of Medicine,Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
-
- Sovijarvi, A. R. A. (författare)
- Department of Pulmonary Medicine, Heart and Lung Center, Helsinki University Central Hospital and University of Helsinki, Finland
-
visa färre...
-
Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Finland Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; Clinic of Thoracic and Occupational Medicine, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway (creator_code:org_t)
- Elsevier BV, 2020
- 2020
- Engelska.
-
Ingår i: Respiratory Medicine. - : Elsevier BV. - 0954-6111 .- 1532-3064. ; 173
- Relaterad länk:
-
https://helda.helsin...
-
visa fler...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- The prevalence of asthma is higher in Sweden and Finland than in neighbouring eastern countries including Estonia. Corresponding difference in bronchial eosinophilic inflammation could be studied by FENO measurements. We aimed to compare FENO in adult general populations of Sweden, Finland, and Estonia, to test the plausibility of the west-east disparity hypothesis of allergic diseases. We conducted clinical interviews (N = 2658) with participants randomly selected from the general populations in Sweden (Stockholm and dOrebro), Finland (Helsinki), and Estonia (Narva and Saaremaa), and performed FENO (n = 1498) and skin prick tests (SPT) in 1997-2003. The median (interquartile range) of FENO (ppb) was 15.5 (9.3) in Sweden, 15.4 (13.6) in Finland and 12.5 (9.6) in Estonia. We found the lowest median FENO values in the Estonian centres Saaremaa 13.1 (9.5) and Narva 11.8 (8.6). In the pooled population, asthma was associated with FENO >= 25 ppb, odds ratio (OR) 3.91 (95% confidence intervals: 2.29-6.32) after adjusting for SPT result, smoking, gender and study centre. A positive SPT test increased the likelihood of asthma OR 3.19 (2.02-5.11). Compared to Saaremaa, the likelihood of having asthma was higher in Helsinki OR 2.40 (1.04-6.02), Narva OR 2.45 (1.05-6.19), dOrebro OR 3.38 (1.59-8.09), and Stockholm OR 5.54 (2.18-14.79). There was a higher prevalence of asthma and allergic airway inflammation in adult general populations of Sweden and Finland compared to those of Estonia. Atopy and elevated FEND level were independently associated with an increased risk of asthma. In conclusion, the findings support the earlier west-east disparity hypothesis of allergic diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Nyckelord
- Asthma
- FENO
- Atopy
- Skin prick test
- exhaled nitric-oxide
- increasing prevalence
- common allergens
- sensitization
- symptoms
- disorders
- childhood
- helsinki
- fraction
- diseases
- Cardiovascular System & Cardiology
- Respiratory System
- Asthma
- Nursing
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Lassmann-Klee, P ...
-
Piirilla, P. L.
-
Brumpton, B.
-
Larsson, Matz, 1 ...
-
Sundblad, B. M.
-
Polluste, J.
-
visa fler...
-
Juusela, M.
-
Routious, A.
-
Mere, M.
-
Lindqvist, A.
-
Kankaanranta, Ha ...
-
Backman, Helena
-
Langhammer, A.
-
Rönmark, Eva
-
Lundbäck, Bo, 19 ...
-
Sovijarvi, A. R. ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kardiologi
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Lungmedicin och ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Omvårdnad
- Artiklar i publikationen
-
Respiratory Medi ...
- Av lärosätet
-
Göteborgs universitet
-
Örebro universitet
-
Umeå universitet
-
Luleå tekniska universitet
-
Karolinska Institutet