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The association of ...
The association of severe anemia, red blood cell transfusion and necrotizing enterocolitis in neonates
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Song, J. (författare)
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Dong, H. M. (författare)
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Xu, F. L. (författare)
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Wang, Y. (författare)
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Li, W. D. (författare)
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Jue, Z. Z. (författare)
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Wei, L. L. (författare)
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Yue, Y. Y. (författare)
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- Zhu, Changlian, 1964 (författare)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering,Institute of Neuroscience and Physiology, Department of Health and Rehabilitation
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(creator_code:org_t)
- 2021-07-20
- 2021
- Engelska.
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Ingår i: Plos One. - : Public Library of Science (PLoS). - 1932-6203. ; 16:7
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- Background The relationship between severe anemia, red blood cell transfusion and Neonatal necrotizing enterocolitis (NEC) remains controversial. The purpose of this study was to determine the association of severe anemia and RBC transfusion with NEC in neonates. Methods The clinical characteristics of NEC were observed in 467 infants with different birth weights from January 2012 to July 2020. A 1:1 ratio case-control study was performed in very low birth weight (VLBW) infants. Severe anemia, RBC transfusion, and confounding factors, including maternal and perinatal complications, feeding, and antibiotics administration were collected in both groups. Univariate and multivariate analyses were used to investigate effects on the risk of NEC. Results The day of NEC onset and mortality were inversely associated with birth weight. In VLBW infants, adjusting for other factors, severe anemia within 72 h [OR = 2.404, P = 0.016], RBC transfusion within 24 h [OR = 4.905, P = 0.016], within 48 h [OR = 5.587, P = 0.008], and within 72 h [OR = 2.858, P = 0.011] increased the risk of NEC. Conclusion Both severe anemia and RBC transfusion appears to increase the risk of NEC in VLBW infants. The early prevention and treatment of anemia, strict evaluation of the indications for transfusion and enhanced monitoring after transfusion is encouraged in the NICU.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- birth-weight infants
- premature-infants
- risk-factors
- care
- Science & Technology - Other Topics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
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Plos One
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Till lärosätets databas
- Av författaren/redakt...
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Song, J.
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Dong, H. M.
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Xu, F. L.
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Wang, Y.
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Li, W. D.
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Jue, Z. Z.
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visa fler...
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Wei, L. L.
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Yue, Y. Y.
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Zhu, Changlian, ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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och Neurovetenskaper
- Artiklar i publikationen
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Plos One
- Av lärosätet
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Göteborgs universitet
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Karolinska Institutet