Sökning: onr:"swepub:oai:gup.ub.gu.se/317590" > A prospective 5-yea...
Fältnamn | Indikatorer | Metadata |
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000 | 04192naa a2200421 4500 | |
001 | oai:gup.ub.gu.se/317590 | |
003 | SwePub | |
008 | 240528s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/3175902 URI |
024 | 7 | a https://doi.org/10.1080/00016489.2022.20862912 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Aghajanzadeh, Susanu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xaghsu |
245 | 1 0 | a A prospective 5-year study of trismus prevalence and fluctuation in irradiated head and neck cancer patients |
264 | c 2022-07-26 | |
264 | 1 | b Informa UK Limited,c 2022 |
520 | a Background Trismus is a complication post-radiotherapy for head and neck cancer (HNC), which causes pain, eating limitations and reduced quality-of-life. However, little is known about the condition long-term or how trismus fluctuates within an irradiated population. Aim/Objective To prospectively map trismus prevalence in irradiated HNC patients up to 5-years following treatment completion including describing intra-group fluctuation of maximum interincisal opening (MIO). Materials and Methods 211 patients receiving curatively intended radiotherapy for HNC were included in this prospective study. Patients were followed pre-radiotherapy (baseline), 3-, 6-, 12-, 24-, 36- and 60-months post-radiotherapy completion using MIO. Results Mean MIO at baseline, 12-months and 5-years following radiotherapy were 51.5 mm, 41.7 mm and 41.3 mm respectively. A total of 28% (n = 36) fulfilled the trismus criterion at 5-years post-radiotherapy. Eighty percent of patients (n = 24) with trismus at 5 years post-radiotherapy also suffered from trismus at 12 months post-radiotherapy, whilst 88-92% of all patients reported reduced MIO at any given timepoint compared to baseline. 15% of patients never exceeded an MIO of >35 mm at any time-point. Conclusion Trismus is a prevalent long-term complication of HNC and its treatment, which does not appear to heal spontaneously. The majority of fluctuations in MIO occur during the first 12 months post-radiotherapy completion. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng |
653 | a Radiotherapy | |
653 | a head and neck neoplasm | |
653 | a trismus | |
653 | a quality-of-life | |
653 | a concurrent chemoradiotherapy | |
653 | a radiotherapy | |
653 | a impact | |
653 | a Otorhinolaryngology | |
700 | 1 | a Karlsson, Therese,d 1987u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xkathv |
700 | 1 | a Engström, My,d 1977u Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences4 aut0 (Swepub:gu)xsvemy |
700 | 1 | a Tuomi, Lisa,d 1985u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xtuoli |
700 | 1 | a Finizia, Caterina,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xfinca |
710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar4 org |
773 | 0 | t Acta Oto-Laryngologicad : Informa UK Limitedg 142:7-8, s. 620-626q 142:7-8<620-626x 0001-6489x 1651-2251 |
856 | 4 8 | u https://gup.ub.gu.se/publication/317590 |
856 | 4 8 | u https://doi.org/10.1080/00016489.2022.2086291 |
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