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Adverse events asso...
Adverse events associated with microsurgial treatment for ruptured intracerebral aneurysms: a prospective nationwide study on subarachnoid haemorrhage in Sweden
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- Baldvinsdóttir, Bryndís (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Kronvall, Erik (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Ronne-Engström, Elisabeth (författare)
- Uppsala University,Uppsala universitet,Neurokirurgi,Uppsala Univ, Sweden
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- Enblad, Per (författare)
- Uppsala University,Uppsala universitet,Neurokirurgi,Uppsala Univ, Sweden
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- Lindvall, Peter (författare)
- Umeå University,Umeå universitet,Neurovetenskaper,Umeå Univ, Dept Clin Sci, Neurosurg, Umeå, Sweden.
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- Aineskog, Helena (författare)
- Umeå University,Umeå universitet,Neurovetenskaper,Umeå Univ, Dept Clin Sci, Neurosurg, Umeå, Sweden.
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- Fridriksson, Steen (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Clinical Neuroscience, Neurosurgery, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Dept Clin Neurosci, Neurosurg, Gothenburg, Sweden.
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- Klurfan, Paula (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Clinical Neuroscience, Neurosurgery, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Dept Clin Neurosci, Neurosurg, Gothenburg, Sweden.
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- Svensson, M. (författare)
- Karolinska Institute
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- Alpkvist, P. (författare)
- Karolinska Institute
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- Hillman, Jan, 1952- (författare)
- Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Neurokirurgiska kliniken US
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- Eneling, Johanna (författare)
- Linköping University,Linköpings universitet,Medicinska fakulteten,Avdelningen för kirurgi, ortopedi och onkologi
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- Nilsson, Ola G. (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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(creator_code:org_t)
- 2023-03-17
- 2023
- Engelska.
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Ingår i: Journal of Neurology Neurosurgery and Psychiatry. - : BMJ. - 0022-3050 .- 1468-330X. ; 94:7, s. 575-580
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Abstract
Ämnesord
Stäng
- BackgroundAdverse events (AEs) or complications may arise secondary to the treatment of aneurysmal subarachnoid haemorrhage (SAH). The aim of this study was to identify AEs associated with microsurgical occlusion of ruptured aneurysms, as well as to analyse their risk factors and impact on functional outcome. MethodsPatients with aneurysmal SAH admitted to the neurosurgical centres in Sweden were prospectively registered during a 3.5-year period (2014-2018). AEs were categorised as intraoperative or postoperative. A range of variables from patient history and SAH characteristics were explored as potential risk factors for an AE. Functional outcome was assessed approximately 1 year after the bleeding using the extended Glasgow Outcome Scale. ResultsIn total, 1037 patients were treated for ruptured aneurysms, of which, 322 patients were treated with microsurgery. There were 105 surgical AEs in 97 patients (30%); 94 were intraoperative AEs in 79 patients (25%). Aneurysm rerupture occurred in 43 patients (13%), temporary occlusion of the parent artery >5 min in 26 patients (8%) and adjacent vessel injury in 25 patients (8%). High Fisher grade and brain oedema on CT were related to increased risk of AEs. At follow-up, 38% of patients had unfavourable outcome. Patients suffering AEs were more likely to have unfavourable outcome (OR 2.3, 95% CI 1.10 to 4.69). ConclusionIntraoperative AEs occurred in 25% of patients treated with microsurgery for ruptured intracerebral aneurysm in this nationwide survey. Although most operated patients had favourable outcome, AEs were associated with increased risk of unfavourable outcome.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- subarachnoid haemorrhage
- cerebrovascular disease
- neurosurgery
- intracranial aneurysms
- case-fatality
- risk-factors
- complications
- predictors
- Neurosciences & Neurology
- Psychiatry
- Surgery
- Cerebrovascular Disease
- CEREBROVASCULAR DISEASE
- NEUROSURGERY
- SUBARACHNOID HAEMORRHAGE
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Baldvinsdóttir, ...
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Kronvall, Erik
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Ronne-Engström, ...
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Enblad, Per
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Lindvall, Peter
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Aineskog, Helena
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visa fler...
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Fridriksson, Ste ...
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Klurfan, Paula
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Svensson, M.
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Alpkvist, P.
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Hillman, Jan, 19 ...
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Eneling, Johanna
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Nilsson, Ola G.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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och Neurovetenskaper
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
- Artiklar i publikationen
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Journal of Neuro ...
- Av lärosätet
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Göteborgs universitet
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Umeå universitet
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Uppsala universitet
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Linköpings universitet
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Lunds universitet
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Karolinska Institutet