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Agreement between r...
Agreement between rapid antigen detection test and culture for group A streptococcus in patients recently treated for pharyngotonsillitis-a prospective observational study in primary care
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- Rystedt, Karin (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,CARe - Centrum för antibiotikaresistensforskning,Institute of Medicine, School of Public Health and Community Medicine,Centre for antibiotic resistance research, CARe,Sahlgrenska Academy,Primary Hlth Care, Sweden; Univ Gothenburg, Sweden; Univ Gothenburg, Sweden; Narhalsan Hentorp Hlth Care Ctr, Sweden; Primary Hlth Care Res & Dev Ctr Skaraborg, Sweden
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- Hedin, Katarina (författare)
- Linköpings universitet,Linköping University,Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Jönköping county,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Futurum, Region Jonkoping, Sweden; Lund Univ, Sweden
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- Tyrstrup, Mia (författare)
- Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Lund Univ, Sweden
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- Skoog-Stahlgren, G. (författare)
- Public Health Agency of Sweden
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- Edlund, C. (författare)
- Public Health Agency of Sweden
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- Giske, C. G. (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska University Hospital,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Gunnarsson, Ronny K, 1955 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,CARe - Centrum för antibiotikaresistensforskning,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Centre for antibiotic resistance research, CARe,Institute of Medicine, School of Public Health and Community Medicine,Sahlgrenska Academy,Primary Hlth Care, Sweden; Univ Gothenburg, Sweden; Univ Gothenburg, Sweden
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- Sundvall, Pär-Daniel (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,CARe - Centrum för antibiotikaresistensforskning,Institute of Medicine, School of Public Health and Community Medicine,Centre for antibiotic resistance research, CARe,Sahlgrenska Academy,Primary Hlth Care, Sweden; Univ Gothenburg, Sweden; Univ Gothenburg, Sweden
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(creator_code:org_t)
- 2023-03-07
- 2023
- Engelska.
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Ingår i: Scandinavian Journal of Primary Health Care. - : Informa UK Limited. - 0281-3432 .- 1502-7724. ; 41:1, s. 91-97
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Abstract
Ämnesord
Stäng
- ObjectiveThe aim was to compare rapid antigen detection test (RADT) and throat culture for group A streptococci (GAS) among patients recently treated with penicillin V for GAS pharyngotonsillitis.Design and settingThe study was a secondary analysis within a randomized controlled trial comparing 5 versus 10 days of penicillin V for GAS pharyngotonsillitis. Patients were recruited at 17 primary health care centres in Sweden.SubjectsWe included 316 patients >= 6 years of age, having 3-4 Centor criteria, a positive RADT and a positive throat culture for GAS at inclusion, and also having a RADT and throat culture for GAS taken at a follow-up visit within 21 days.Main outcome measuresRADT and conventional throat culture for GAS.ResultsThis prospective study showed 91% agreement between RADT and culture at follow-up within 21 days. Only 3/316 participants had negative RADT with a positive throat culture for GAS at follow-up, and 27/316 patients with positive RADT had a negative culture for GAS. Log rank test did not reveal any difference in the decline over time of positive tests between RADT and throat culture (p = 0.24). Agreement between RADT and throat culture for GAS at the follow-up was not associated with treatment duration, number of days from inclusion until follow-up, throat symptoms at follow-up, gender, or age.ConclusionRADT and culture for GAS agreed to a high extent also after recent penicillin V treatment. RADT for GAS means a low risk for missing the presence of GAS.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Streptococcal pharyngotonsillitis
- rapid antigen detection test
- primary care
- Streptococcal pharyngotonsillitis; rapid antigen detection test; primary care
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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