Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries

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Razavi, Homie A.Center for Disease Analysis Foundation, Lafayette, United States,Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; Department of Gastroenterology, Humanitas Research Hospital IRCCS, Rozzano, Italy (författare)

Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries

Artikel/kapitelEngelska2023

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Elsevier,2023

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LIBRIS-ID:oai:gup.ub.gu.se/335374
https://gup.ub.gu.se/publication/335374URI
https://doi.org/10.1016/j.jhep.2023.02.041DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:153620456URI
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-112244URI

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Hepatitis D virus (HDV) infection occurs as a coinfection with hepatitis B and increases the risk of hepatocellular carcinoma, decompensated cirrhosis, and mortality compared to hepatitis B virus (HBV) monoinfection. Reliable estimates of the prevalence of HDV infection and disease burden are essential to formulate strategies to find coinfected individuals more effectively and efficiently. The global prevalence of HBV infections was estimated to be 262,240,000 in 2021. Only 1,994,000 of the HBV in-fections were newly diagnosed in 2021, with more than half of the new diagnoses made in China. Our initial estimates indicated a much lower prevalence of HDV antibody (anti-HDV) and HDV RNA positivity than previously reported in published studies. Ac-curate estimates of HDV prevalence are needed. The most effective method to generate estimates of the prevalence of anti-HDV and HDV RNA positivity and to find undiagnosed individuals at the national level is to implement double reflex testing. This re-quires anti-HDV testing of all hepatitis B surface antigen-positive individuals and HDV RNA testing of all anti-HDV-positive in-dividuals. This strategy is manageable for healthcare systems since the number of newly diagnosed HBV cases is low. At the global level, a comprehensive HDV screening strategy would require only 1,994,000 HDV antibody tests and less than 89,000 HDV PCR tests. Double reflex testing is the preferred strategy in countries with a low prevalence of HBV and those with a high prevalence of both HBV and HDV. For example, in the European Union and North America only 35,000 and 22,000 cases, respectively, will require anti-HDV testing annually.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Gastroenterologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Gastroenterology and Hepatology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Infektionsmedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Infectious Medicine hsv//eng
Hepatitis D virus
HDV
HDV

Biuppslag (personer, institutioner, konferenser, titlar ...)

Buti, MariaLiver Unit, Hospital Universitari Vall d Hebron and CIBEREHD del Insituto Carlos III. Universidad Autonoma de Barcelona, Barcelona, Spain (författare)
Terrault, Norah A.Keck Medicine of University of Southern California, Los Angeles, United States (författare)
Zeuzem, StefanDepartment of Medicine, University Hospital, Frankfurt, Germany (författare)
Yurdaydin, CihanDepartment of Gastroenterology and Hepatology, Koç University Medical School, Istanbul, Turkey (författare)
Tanaka, JunkoEpidemiology, Infectious Disease Control and Prevention, Hiroshima University, Hiroshima, Japan (författare)
Aghemo, AlessioDepartment of Clinical Sciences, College of Medicine, Dar Al Uloom University, Riyadh, Saudi Arabia,Division of Infectious Disease, Federal University of Sāo Paulo, Sāo Paulo, Brazil,National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy,Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy (författare)
Akarca, Ulus S.Department of Gastroenterology, Ege University, Medical School, Izmir, Turkey (författare)
Al Masri, Nasser M.Department of Gastroenterology & Hepatology, Prince Sultan Medical Military City (PSMMC), Riyadh, Saudi Arabia (författare)
Alalwan, Abduljaleel M.Department of Hepatobiliary Science and Liver Transplantation King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia (författare)
Aleman, SooKarolinska Institutet,Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden (författare)
Alghamdi, Abdullah S.Gastroenterology Unit/Medical Department, King Fahad General Hospital, Jeddah, Saudi Arabia,Liver & Small Bowel Health Centre Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia (författare)
Alghamdi, Saad (författare)
Al-Hamoudi, Waleed K.Department of Medicine, King Saud University, Riyadh, Saudi Arabia (författare)
Aljumah, Abdulrahman A. (författare)
Altraif, Ibrahim H.Hepatology Division - Hepatobiliary Sciences and Organ Transplant Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia (författare)
Asselah, TarikHepatology Department, University of Paris-Cité, Hôpital Beaujon, AP-HP, INSERM UMR1149, Paris, France (författare)
Ben-Ari, ZivLiver Diseases Center, Sheba Medical Center, Ramat Gan, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel (författare)
Berg, ThomasDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany (författare)
Biondi, Mia J.School of Nursing, York University, Toronto, Canada,Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Mainland (författare)
Blach, SarahEpidemiology, Center for Disease Analysis Foundation, Lafayette, United States (författare)
Braga, Wornei S. M.Virology Department, Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Brazil (författare)
Brandao-Mello, Carlos E.Internal Medicine & Gastroenterology, University of Rio de Janeiro, Rio de Janeiro, Brazil; Clinica de Doenças do Fígado, Rio de Janeiro, Brazil (författare)
Brunetto, Maurizia R.Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; Integrated Department of Medical Specialties, University Hospital of Pisa, Pisa, Italy (författare)
Cabezas, JoaquinGastroenterology and Hepatology Department, Marques de Valdecilla University Hospital, Santander, Spain; Clinical and Translational Research in Digestive Diseases, IDIVAL, Santander, Spain (författare)
Cheinquer, HugoDepartment of Gastroenterology and Hepatology, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil (författare)
Chen, Pei-JerHepatitis Research Center, National Taiwan University, Taipei, Taiwan (författare)
Cheon, Myeong-EunDivision of HIV/AIDS Prevention and Control, Korea Disease Control and Prevention Agency, Osong, Republic of Korea (författare)
Chuang, Wan-LongHepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan (författare)
Coffin, Carla S.Medicine / Microbiology and Infectious Diseases Department, Cumming School of Medicine, University of Calgary, Calgary, Canada (författare)
Coppola, NicolaMental Health and Public Medicine, University of Campania, Naples, Italy (författare)
Craxi, AntonioPROMISE, School of Medicine, University of Palermo, Palermo, Italy (författare)
Crespo, JavierGastroenterology and Hepatology Department, Clinical and Translational Research in Digestive Diseases, Valdecilla Research Institute (IDIVAL), Marqués de Valdecilla University Hospital, Santander, Spain; School of Medicine, University of Cantabria, Santander, Spain (författare)
De Ledinghen, VictorService d'hepatologie et de Transplantation Hepatique, CHU, Bordeaux, France (författare)
Duberg, Ann-Sofi,Docent,1957-Örebro universitet,Institutionen för medicinska vetenskaper(Swepub:oru)adg (författare)
Etzion, OhadDepartment of Gastroenterology and Liver Diseases, Soroka University Medical Center, Beersheva, Israel; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheva, Israel (författare)
Ferraz, Maria Lucia G.Gastroenterology/Hepatology, Federal University of Sao Paulo, São Paulo, Brazil (författare)
Ferreira, Paulo R. A.Department of Medicine, University of British Columbia, Vancouver, Canada (författare)
Forns, XavierLiver Unit, Hospital Clínic. IDIBAPS and CIBEREHD. University of Barcelona., Barcelona, Spain (författare)
Foster, Graham R.Blizard Institute, Barts Liver Centre, Queen Mary University London, London, United Kingdom (författare)
Gaeta, Giovanni B.Infectious Diseases, University Vanvitelli, Napoli, Italy (författare)
Gamkrelidze, IvaneCenter for Disease Analysis Foundation, Lafayette, United States (författare)
Garcia-Samaniego, JavierLiver Unit, Hospital Universitario La Paz, CIBERehd/IdiPAZ. Universidad Autónoma de Madrid, Madrid, Spain (författare)
Gheorghe, Liliana S.Department of Gastroenterology & Hepatology, Carol Davila University of Medicine & Pharmacy, Bucharest, Romania; Department of Gastroenterology & Hepatology, Fundeni Clinical Institute, Bucharest, Romania (författare)
Gholam, Pierre M.Medicine, Case Western Reserve University School of Medicine, Cleveland, United States (författare)
Gish, Robert G.Hepatitis B Foundation, Doylestown, United States (författare)
Glenn, JeffreyMedicine and Microbiology & Immunology, Stanford University, Palo Alto, United States (författare)
Hercun, JulianLiver Unit, Centre Hospitalier de l'Universite de Montreal, Montreal, Canada (författare)
Hsu, Yao-ChunDepartment of Medical Research, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan (författare)
Hu, Ching-ChihGastroenterology and Hepatology, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan (författare)
Huang, Jee-FuHepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan (författare)
Janjua, NaveedBC Centre for Disease Control, Vancouver, Canada (författare)
Jia, JidongDepartment of Medicine, Western University, London, Canada (författare)
Kaberg, MartinKarolinska Institutet,Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden (författare)
Kaita, Kelly D. E.Internal Medicine, Section of Hepatology, University of Manitoba, Winnipeg, Canada (författare)
Kamal, HabibaDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden (författare)
Kao, Jia-HorngHepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan (författare)
Kondili, Loreta A. (författare)
Lagging, Martin,1965Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,Department of Infectious Diseases / Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Microbiology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden(Swepub:gu)xlagma (författare)
Lazaro, PabloIndependent Health Services Researcher, Madrid, Spain (författare)
Lazarus, Jeffrey V.Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain (författare)
Lee, Mei-HsuanInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan (författare)
Lim, Young-SukGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea (författare)
Marotta, Paul J. (författare)
Navas, Maria-CristinaGrupo de Gastrohepatología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia (författare)
Naveira, Marcelo C. M.Center for Disease Analysis Foundation, Lafayette, United States (författare)
Orrego, MauricioGastroenterología y Hepatología, Clínica Las Americas AUNA, Medellín, Colombia; Hepatology Department, Clinica Las Vegas Quiron, Medellin, Colombia (författare)
Osiowy, CarlaViral Hepatitis and Bloodborne Pathogens Department, National Microbiology Lab, Public Health Agency of Canada, Winnipeg, Canada (författare)
Pan, Calvin Q.Division of Gastroenterology and Hepatology, Department of Medicine, NYU Langone Health, NYU Grossman School of Medicine, New York, United States (författare)
Pessoa, Mario G.Division of Gastroenterology and Hepatology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil (författare)
Raimondo, GiovanniDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy (författare)
Ramji, Alnoor (författare)
Razavi-Shearer, Devin M.Center for Disease Analysis Foundation, Lafayette, United States (författare)
Razavi-Shearer, KathrynCenter for Disease Analysis Foundation, Lafayette, United States (författare)
Rios-Hincapie, Cielo Y.Dirección de Promoción y Prevención, Ministerio de Salud y Protección Social, Bogotá, Colombia (författare)
Rodriguez, ManuelLiver Unit. Division of Gastroenterology and Hepatology, Hospital Universitario Central de Asturias, Oviedo, Spain (författare)
Rosenberg, William M. C.Institute for Liver and Digestive Health, Division of Medicine, UCL, London, United Kingdom (författare)
Roulot, Dominique M.APHP, Hopital Avicenne, Unité d'Hépatologie, Université Sorbonne Paris Nord, Bobigny, France (författare)
Ryder, Stephen D.Hepatology, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom (författare)
Safadi, RifaatThe Liver Institute, Hadassah Medical Organization, Jerusalem, Israel (författare)
Sanai, Faisal M.Gastroenterology, King Abdulaziz Medical City, Jeddah, Saudi Arabia (författare)
Santantonio, Teresa A. (författare)
Sarrazin, ChristophMedizinische Klinik 2, St. Josefs-Hospital, Wiesbaden, Germany; Medizinische Klinik 1, Goethe-University, Frankfurt Am Main, Germany (författare)
Shouval, DanielThe Liver Institute, Hadassah Medical Organization, Jerusalem, Israel (författare)
Tacke, FrankDepartment of Hepatology & Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany (författare)
Tergast, Tammo L.Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany (författare)
Villalobos-Salcedo, Juan MiguelResearch Center for Tropical Medicine of Rondônia, Porto Velho, Brazil (författare)
Voeller, Alexis S.Center for Disease Analysis Foundation, Lafayette, United States (författare)
Yang, Hwai-IInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Genomics Research Center, Academia Sinica, Taipei, Taiwan; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Biomedical Translation Research Center, Academia Sinica, Taipei, Taiwan (författare)
Yu, Ming-LungSchool of Medicine, College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver Disease, National Sun Yat-sen University, Kaohsiung, Taiwan; Hepatobiliary Section, Department of Internal Medicine, and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine and Hepatitis Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan (författare)
Zuckerman, EliLiver Unit, Carmel Medical Center, Faculty of Medicine, Technion Institute of Technology, Haifa, Israel (författare)
Center for Disease Analysis Foundation, Lafayette, United StatesDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; Department of Gastroenterology, Humanitas Research Hospital IRCCS, Rozzano, Italy (creator_code:org_t)

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Ingår i:JOURNAL OF HEPATOLOGY: Elsevier79:2, s. 576-5800168-82781600-0641

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Av författaren/redakt...: Razavi, Homie A.; Buti, Maria; Terrault, Norah ...; Zeuzem, Stefan; Yurdaydin, Cihan; Tanaka, Junko; visa fler...; Aghemo, Alessio; Akarca, Ulus S.; Al Masri, Nasser ...; Alalwan, Abdulja ...; Aleman, Soo; Alghamdi, Abdull ...; Alghamdi, Saad; Al-Hamoudi, Wale ...; Aljumah, Abdulra ...; Altraif, Ibrahim ...; Asselah, Tarik; Ben-Ari, Ziv; Berg, Thomas; Biondi, Mia J.; Blach, Sarah; Braga, Wornei S. ...; Brandao-Mello, C ...; Brunetto, Mauriz ...; Cabezas, Joaquin; Cheinquer, Hugo; Chen, Pei-Jer; Cheon, Myeong-Eu ...; Chuang, Wan-Long; Coffin, Carla S.; Coppola, Nicola; Craxi, Antonio; Crespo, Javier; De Ledinghen, Vi ...; Duberg, Ann-Sofi ...; Etzion, Ohad; Ferraz, Maria Lu ...; Ferreira, Paulo ...; Forns, Xavier; Foster, Graham R ...; Gaeta, Giovanni ...; Gamkrelidze, Iva ...; Garcia-Samaniego ...; Gheorghe, Lilian ...; Gholam, Pierre M ...; Gish, Robert G.; Glenn, Jeffrey; Hercun, Julian; Hsu, Yao-Chun; Hu, Ching-Chih; Huang, Jee-Fu; Janjua, Naveed; Jia, Jidong; Kaberg, Martin; Kaita, Kelly D. ...; Kamal, Habiba; Kao, Jia-Horng; Kondili, Loreta ...; Lagging, Martin, ...; Lazaro, Pablo; Lazarus, Jeffrey ...; Lee, Mei-Hsuan; Lim, Young-Suk; Marotta, Paul J.; Navas, Maria-Cri ...; Naveira, Marcelo ...; Orrego, Mauricio; Osiowy, Carla; Pan, Calvin Q.; Pessoa, Mario G.; Raimondo, Giovan ...; Ramji, Alnoor; Razavi-Shearer, ...; Razavi-Shearer, ...; Rios-Hincapie, C ...; Rodriguez, Manue ...; Rosenberg, Willi ...; Roulot, Dominiqu ...; Ryder, Stephen D ...; Safadi, Rifaat; Sanai, Faisal M.; Santantonio, Ter ...; Sarrazin, Christ ...; Shouval, Daniel; Tacke, Frank; Tergast, Tammo L ...; Villalobos-Salce ...; Voeller, Alexis ...; Yang, Hwai-I; Yu, Ming-Lung; Zuckerman, Eli; visa färre...

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