Sökning: onr:"swepub:oai:gup.ub.gu.se/40561" >
Antinuclear antibod...
Antinuclear antibodies in the oldest-old women and men
-
- Nilsson, Bengt-Olof, 1954- (författare)
- Linköpings universitet,Infektionsmedicin,Hälsouniversitetet
-
- Skogh, Thomas, 1952- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Reumatologi,Hälsouniversitetet,Länskliniken för Reumatologi i Östergötland
-
- Ernerudh, Jan, 1952- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Klinisk immunologi,Hälsouniversitetet,Klinisk immunologi och transfusionsmedicin
-
visa fler...
-
- Johansson, Boo (författare)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology,Department of Psychology, Göteborg University, Göteborg, Sweden
-
- Lofgren, S (författare)
- Department of Microbiology, Ryhov Hospital, Jönköping, Sweden
-
- Wikby, A (författare)
- Institute of Gerontology, School of Health Sciences, Jönköping, Sweden
-
- Dahle, Charlotte, 1956- (författare)
- Linköpings universitet,Klinisk immunologi,Hälsouniversitetet
-
visa färre...
-
(creator_code:org_t)
- Elsevier, 2006
- 2006
- Engelska.
-
Ingår i: Journal of Autoimmun. - : Elsevier. ; 27:4, s. 281-288
- Relaterad länk:
-
https://gup.ub.gu.se...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- The aim of this study was to compare the prevalence of antinuclear antibodies (ANA) in very old individuals (>/=86years of age) with healthy younger (18-68years) blood donors (n=200) regarding gender, health status, ratio of circulating CD4/CD8 cells and cytomegalovirus (CMV) serology. Frozen plasma was used for ANA detection in two study groups, i.e. 'OCTO' (97 persons aged 86-92years, 65% women) and 'NONA' (136 persons aged 86-95years, 70% women). OCTO participants were recruited on the basis that they were healthy or moderately healthy according to a selection protocol. No exclusion criteria regarding health status were applied in the NONA sample. The prevalence of ANA was significantly higher in the oldest-old samples compared to blood donors. There was no association between health status and the presence of ANA in the oldest-old. The difference across age was most pro-nounced in men, with low levels at younger age, whereas the prevalence among the oldest-old men reached similar levels as in women. There were no associations between the presence of ANA and CD4/CD8 ratio or with CMV status in the oldest-old. Our findings confirm an in-creased prevalence of ANA in the oldest-old, and emphasize the importance of taking gender and age into consideration when evaluating ANA.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- antinuclear antibody
- CD4/CD8
- CMV
- middle-aged
- oldest-old
- MEDICINE
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas