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Effects on cycle co...
Effects on cycle control and bodyweight of the combined contraceptive ring, NuvaRing, versus an oral contraceptive containing 30 microg ethinyl estradiol and 3 mg drospirenone
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- Milsom, Ian, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
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Lete, I (författare)
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Bjertnaes, A (författare)
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visa fler...
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Rokstad, K (författare)
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- Lindh, Ingela, 1954 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
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Gruber, C J (författare)
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Birkhauser, M H (författare)
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Aubeny, E (författare)
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Knudsen, T (författare)
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Bastianelli, C (författare)
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visa färre...
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(creator_code:org_t)
- 2006
- 2006
- Engelska.
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Ingår i: Hum Reprod. ; 21:9, s. 2304-11
- Relaterad länk:
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https://gup.ub.gu.se...
Abstract
Ämnesord
Stäng
- BACKGROUND: The objective of this study was to compare cycle control, cycle-related characteristics and bodyweight effects of NuvaRing with those of a combined oral contraceptive (COC) containing 30 microg of ethinyl estradiol and 3 mg of drospirenone. METHODS: A randomized, multicentre, open-label trial in which 983 women were treated (intent-to-treat population) with NuvaRing or the COC for 13 cycles. RESULTS: Breakthrough bleeding or spotting during cycles 2-13 was in general less frequent with NuvaRing than that with the COC (4.7-10.4%) and showed a statistically significant odds ratio of 0.61 (95% confidence interval: 0.46, 0.80) with longitudinal analysis. Intended bleeding was significantly better for all cycles with NuvaRing (55.2-68.5%) than that with the COC (35.6-56.6%) (P < 0.01). Changes from baseline in mean bodyweight and body composition parameters were relatively small for both groups with no notable between-group differences. CONCLUSION: NuvaRing was associated with better cycle control than the COC, and there was no clinically relevant difference between the two groups in bodyweight.
Nyckelord
- Administration
- Oral
- Adult
- Androstenes/*administration & dosage
- Body Composition
- Body Weight
- *Contraceptive Devices
- Female
- Contraceptives
- Oral/*therapeutic use
- Desogestrel/*administration & dosage/analogs & derivatives
- Drug Combinations
- Ethinyl Estradiol/*administration & dosage
- Humans
- *Intrauterine Devices
- Menstrual Cycle/*drug effects
- Patient Compliance
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Milsom, Ian, 195 ...
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Lete, I
-
Bjertnaes, A
-
Rokstad, K
-
Lindh, Ingela, 1 ...
-
Gruber, C J
-
visa fler...
-
Birkhauser, M H
-
Aubeny, E
-
Knudsen, T
-
Bastianelli, C
-
visa färre...
- Artiklar i publikationen
- Hum Reprod
- Av lärosätet
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Göteborgs universitet