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T vector and loop c...
T vector and loop characteristics in coronary artery disease and during acute ischemia
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Rubulis, Aigars, 1974 (författare)
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Jensen, J. (författare)
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Lundahl, G. (författare)
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visa fler...
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Tapanainen, J. (författare)
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Wecke, L. (författare)
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- Bergfeldt, Lennart, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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visa färre...
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(creator_code:org_t)
- 2004
- 2004
- Engelska.
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Ingår i: Heart Rhythm. - 1547-5271. ; 1:3, s. 317-25
- Relaterad länk:
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https://gup.ub.gu.se...
Abstract
Ämnesord
Stäng
- OBJECTIVE: Three-dimensional characterization of the ventricular repolarization by the T vector and T vector loop morphology in coronary artery disease (CAD), and their response to short-term (no flow) ischemia induced by coronary occlusion during a percutaneous intervention (PCI). BACKGROUND: The risk for sudden cardiac death is increased in conditions of acute or permanently heterogeneous ventricular repolarization, for which ischemia is a risk factor. METHODS: Fifty-six CAD patients without visible collateral circulation were studied during an elective single-vessel PCI, and 10 healthy controls twice at rest. T vector parameters (Televation, Tazimuth, and QRS-T angle), and T loop parameters (Tarea, Tavplan, and Teigenv) were measured by vectorcardiography. ST vector magnitude (ST-VM) and its change (STC-VM) were used for reference. RESULTS: At rest, T vector loop morphology (Tarea, Teigenv) was significantly different in CAD patients and controls, while T vector angles did not separate the groups. Ischemia induced significant changes in T loop parameters in the entire CAD group, whereas in the LAD subgroup significant changes were seen also in T vector angle. The T loop morphology was significantly different at baseline and a more pronounced response to ischemia (Tarea) was seen in patients with, than in those without, a history of hypertension. CONCLUSION: T loop morphology, rather than the T vector angle, separated CAD patients from healthy controls. Coronary occlusion had significant impact on ventricular repolarization, as assessed by T vector and morphology analysis, and most prominently in the LAD group. Hypertensive patients appeared especially vulnerable to ischemia.
Nyckelord
- Acute Disease
- Adult
- Aged
- *Angioplasty
- Transluminal
- Percutaneous Coronary/adverse effects
- Case-Control Studies
- Coronary Arteriosclerosis/diagnosis/*physiopathology
- Female
- Humans
- Male
- Middle Aged
- Myocardial Ischemia/diagnosis/etiology/*physiopathology
- Predictive Value of Tests
- Reproducibility of Results
- *Vectorcardiography
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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