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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04941naa a2200889 4500 | |
| 001 | oai:gup.ub.gu.se/54598 | |
| 003 | SwePub | |
| 008 | 240528s2005 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:d8b31090-9678-4520-9b45-9244a2474d44 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/545982 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1600-0501.2004.01151.x2 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/2269672 URI |
| 040 | a (SwePub)gud (SwePub)lu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Balatsouka, Dimitra4 aut |
| 245 | 1 0 | a The impact of nicotine on osseointegration. An experimental study in the femur and tibia of rabbits. |
| 264 | c 2005-08-19 | |
| 264 | 1 | b Wiley,c 2005 |
| 520 | a OBJECTIVES: The aim of the present study was to analyze the effect of an enhanced systematic dose of nicotine on osseointegration of titanium implants. MATERIAL AND METHODS: Sixteen female rabbits received either nicotine (n=8) or saline (n=8) administered subcutaneously via mini-osmotic pumps for 2 months. The pump delivered 6 mug/kg/min of nicotine for the animals in the test group. Blood was withdrawn and plasma cotinine levels were measured weekly. Thirty-two titanium implants were inserted into the femur and tibia of all rabbits after 4 weeks and after 6 weeks of nicotine/placebo exposure. Thus, 2- and 4-week healing groups were created. Biomechanical evaluation by (i) resonance frequency analysis test (RFA) on all implants after insertion and before sacrifice and (ii) removal torque test (RMT) on tibial implants before sacrifice was performed. All implants placed in the femur were processed to undecalcified ground sections. The percentage of bone-to-implant contact (BIC) and of bone area within the threads (BD-i) were measured. RESULTS: No significant difference in RMT and RFA values was found between the test and the control group. Histomorphometric measurements of the BIC and the peri-implant BD-i showed no significant differences between the test and the control group after 2 or after 4 weeks. CONCLUSION: Nicotine exposure for a short period of time even in a high dose did not have a significant impact on implant osseointegration in rabbits. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng |
| 653 | a Animals | |
| 653 | a Biomechanics | |
| 653 | a Cotinine | |
| 653 | a blood | |
| 653 | a Dental Implants | |
| 653 | a Female | |
| 653 | a Femur | |
| 653 | a drug effects | |
| 653 | a pathology | |
| 653 | a Fluorescent Dyes | |
| 653 | a diagnostic use | |
| 653 | a Ganglionic Stimulants | |
| 653 | a administration & dosage | |
| 653 | a pharmacology | |
| 653 | a Infusion Pumps | |
| 653 | a Injections | |
| 653 | a Subcutaneous | |
| 653 | a Nicotine | |
| 653 | a administration & dosage | |
| 653 | a pharmacology | |
| 653 | a Osseointegration | |
| 653 | a drug effects | |
| 653 | a Placebos | |
| 653 | a Rabbits | |
| 653 | a Stress | |
| 653 | a Mechanical | |
| 653 | a Surface Properties | |
| 653 | a Tibia | |
| 653 | a drug effects | |
| 653 | a pathology | |
| 653 | a Titanium | |
| 653 | a chemistry | |
| 653 | a Torque | |
| 653 | a Vibration | |
| 653 | a test | |
| 653 | a removal torque | |
| 653 | a nicotine | |
| 653 | a implants | |
| 653 | a bone healing | |
| 653 | a histomorphometry | |
| 653 | a resonance frequency analysis | |
| 653 | a smoking | |
| 700 | 1 | a Gotfredsen, Klaus4 aut |
| 700 | 1 | a Lindh, Christianu Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)ymed-cli |
| 700 | 1 | a Berglundh, Tord,d 1954u Gothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för parodontologi,Institute of Odontology, Department of Periodontology4 aut0 (Swepub:gu)xbetor |
| 710 | 2 | a Avdelningen för arbets- och miljömedicinb Institutionen för laboratoriemedicin4 org |
| 773 | 0 | t Clinical oral implants researchd : Wileyg 16:4, s. 389-95q 16:4<389-95x 0905-7161x 1600-0501 |
| 856 | 4 | u http://dx.doi.org/10.1111/j.1600-0501.2004.01151.xy FULLTEXT |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/54598 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1600-0501.2004.01151.x |
| 856 | 4 8 | u https://lup.lub.lu.se/record/226967 |
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