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Links between tempe...
Links between temperamental dimensions and brain monoamines in the rat
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- Hansen, Stefan, 1953 (författare)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology
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- Ray, Jeremy, 1969 (författare)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology
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Waters, Nicholas (författare)
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(creator_code:org_t)
- 2006
- 2006
- Engelska.
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Ingår i: Behavioral Neuroscience. - : American Psychological Association (APA). - 0735-7044 .- 1939-0084. ; 120:1, s. 85-92
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In 27 female Wistar rats we obtained composite scores on harm avoidance and novelty seeking, as well as 57 measures of monoamines and metabolites from 10 different brain regions. A multivariate regression method was used to discover associations between individual differences in temperament and neurochemistry. Harm avoidant subjects had low levels of striatal dopamine, and high levels of cortical norepinephrine and amygdaloid 5-hydroxyindoleacetic acid. High novelty seeking scores were linked to low levels of brainstem serotonin and dopamine, and to low levels of 5-hydroxyindoleacetic acid in amygdala and accumbens. Moreover, rats scoring high on novelty seeking had higher-than-average levels of norepinephrine in the thalamus and amygdala, and of serotonin in the amygdala.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- brain monoamines
- Temperament
- nucleus-accumbens
- novelty seeking
- harm avoidance
- personality-traits
- ventral striatum
- neuron number
- clinical-data
- dopamine
- model
- microdialysis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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