Asperger syndrome: familial and pre- and perinatal factors.

• OBJECTIVE: Study familial and pre- and perinatal factors in Asperger Syndrome (AS). METHODS: One hundred boys with AS had their records reviewed. "Pathogenetic subgroups" were defined according to presence of medical syndromes/chromosomal abnormalities, indices of familiality, and pre- and perinatal risk factors predisposing to brain damage. RESULTS: No major index of pathogenetic factors was found in 13%, a syndrome/chromosomal abnormality in 8%, pre- or perinatal risk 13%, combined pre- or perinatal risk and family history in 11%, and family history only in 55%. COMMENT: About 50% of all boys with AS have a paternal family history of autism spectrum disorder. Pre- and perinatal risks appear to be important in about 25% of cases.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Adolescent

Asperger Syndrome

Diagnosis

Etiology

Genetics

Child of Impaired Parents

Statistics & numerical data

Chromosome Aberrations

Diagnostic and Statistical Manual of Mental Disorders

Female

Humans

Male

Medical Records

Perinatology

Pregnancy

Pregnancy Complications

Wechsler Scales

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)