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Psychosocial factor...
Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men
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Rosengren, Annika, 1951 (författare)
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Freden, M. (författare)
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Hansson, Per-Olof, 1958 (författare)
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- Wilhelmsen, Lars, 1932 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine
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Wedel, H. (författare)
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Eriksson, Henry, 1946 (författare)
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(creator_code:org_t)
- Elsevier BV, 2008
- 2008
- Engelska.
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Ingår i: Journal of Thrombosis and Haemostasis. - : Elsevier BV. - 1538-7836. ; 6:4, s. 558-64
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The link between psychosocial factors and coronary heart disease is well established, but although effects on coagulation and fibrinolysis variables may be implicated, no population-based study has sought to determine whether venous thromboembolism is similarly related to psychosocial factors. OBJECTIVE: To determine whether venous thromboembolism (deep vein thrombosis or pulmonary embolism) is related to psychosocial factors. PATIENTS/METHODS: A stress questionnaire was filled in by 6958 men at baseline from 1970 to 1973, participants in a cardiovascular intervention trial. Their occupation was used to determine socio-economic status. RESULTS: After a maximum follow-up of 28.8 years, 358 cases of deep vein thrombosis and/or pulmonary embolism were identified through the Swedish hospital discharge and cause-specific death registries. In comparison with men who, at baseline, had no or moderate stress, men with persistent stress had increased risk of pulmonary embolism [hazard ratio (HR)=1.80, 95% CI: 1.21-2.67]. After multivariable adjustment, the HR decreased slightly to 1.66 (95% CI: 1.12-2.48). When compared with manual workers, men with white-collar jobs at intermediate or high level and professionals showed an inverse relationship between occupational class and pulmonary embolism (multiple-adjusted HR=0.57, 95% CI: 0.39-0.83). Deep vein thrombosis was not significantly related to either stress or occupational class. CONCLUSION: Both persistent stress and low occupational class were independently related to future pulmonary embolism. The mechanisms are unknown, but effects on coagulation and fibrinolytic factors are likely.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Aged
- 80 and over
- Alcoholism/epidemiology
- Body Mass Index
- Cardiovascular Diseases/mortality
- Confounding Factors (Epidemiology)
- Diabetes Mellitus/epidemiology
- Follow-Up Studies
- Humans
- Hyperlipidemias/epidemiology
- Hypertension/epidemiology
- Intervention Studies
- Leisure Activities
- Male
- Neoplasms/mortality
- Occupations/statistics & numerical data
- Proportional Hazards Models
- Pulmonary Embolism/*epidemiology/etiology/psychology
- Questionnaires
- Risk Factors
- Smoking/epidemiology
- Social Class
- Stress
- Psychological/*epidemiology
- Sweden/epidemiology
- Thrombophlebitis/*epidemiology/etiology/psychology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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