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Acute echocardiogra...
Acute echocardiographic and hemodynamic response to his-bundle pacing in patients with first-degree atrioventricular block
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- Loring, Zak (författare)
- Duke Clinical Research Institute (DCRI),Duke University
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- Holmqvist, Fredrik (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Clinical studies af Atrial Fibrillation,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Duke University
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- Sze, Edward (författare)
- Maine Medical Center,Duke University
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- Alenezi, Fawaz (författare)
- Duke University
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- Campbell, Kristen (författare)
- Maine Medical Center,Duke University Medical Center
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- Koontz, Jason I. (författare)
- Duke University
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- Velazquez, Eric J. (författare)
- Yale University,Duke University
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- Atwater, Brett D. (författare)
- Duke University,Inova Heart and Vascular Institute
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- Bahnson, Tristram D. (författare)
- Duke University
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- Daubert, James P. (författare)
- Duke University
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(creator_code:org_t)
- 2022-04-21
- 2022
- Engelska.
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Ingår i: Annals of Noninvasive Electrocardiology. - : Wiley. - 1082-720X .- 1542-474X. ; 27:4
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Atrial pacing and right ventricular (RV) pacing are both associated with adverse outcomes among patients with first-degree atrioventricular block (1°AVB). His-bundle pacing (HBP) provides physiological activation of the ventricle and may be able to improve both atrioventricular (AV) and inter-ventricular synchrony in 1°AVB patients. This study evaluates the acute echocardiographic and hemodynamic effects of atrial, atrial-His-bundle sequential (AH), and atrial-ventricular (AV) sequential pacing in 1°AVB patients. Methods: Patients with 1°AVB undergoing atrial fibrillation ablation were included. Following left atrial (LA) catheterization, patients underwent atrial, AH- and AV-sequential pacing. LA/left ventricular (LV) pressure and echocardiographic measurements during the pacing protocols were compared. Results: Thirteen patients with 1°AVB (mean PR 221 ± 26 ms) were included. The PR interval was prolonged with atrial pacing compared to baseline (275 ± 73 ms, p =.005). LV ejection fraction (LVEF) was highest during atrial pacing (62 ± 11%), intermediate with AH-sequential pacing (59 ± 7%), and lowest with AV-sequential pacing (57 ± 12%) though these differences were not statistically significant. No significant differences were found in LA or LV mean pressures or LV dP/dT. LA and LV volumes, isovolumetric times, electromechanical delays, and global longitudinal strains were similar across pacing protocols. Conclusion: Despite pronounced PR prolongation, the acute effects of atrial pacing were not significantly different than AH- or AV-sequential pacing. Normalizing atrioventricular and/or inter-ventricular dyssynchrony did not result in acute improvements in cardiac output or loading conditions.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- echocardiography
- EP study
- first-degree AV-block
- His-bundle
- pacing
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Loring, Zak
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Holmqvist, Fredr ...
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Sze, Edward
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Alenezi, Fawaz
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Campbell, Kriste ...
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Koontz, Jason I.
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visa fler...
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Velazquez, Eric ...
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Atwater, Brett D ...
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Bahnson, Tristra ...
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Daubert, James P ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Annals of Noninv ...
- Av lärosätet
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Lunds universitet