Sökning: onr:"swepub:oai:lup.lub.lu.se:13298810-6eb4-4c19-86cb-1cb30a448886" > Emerging roles of i...
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001 | oai:lup.lub.lu.se:13298810-6eb4-4c19-86cb-1cb30a448886 | |
003 | SwePub | |
008 | 171228s2018 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:138023316 | |
024 | 7 | a https://lup.lub.lu.se/record/13298810-6eb4-4c19-86cb-1cb30a4488862 URI |
024 | 7 | a https://doi.org/10.1111/all.133402 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1380233162 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a for2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Kortekaas Krohn, I.u Catholic University of Leuven4 aut |
245 | 1 0 | a Emerging roles of innate lymphoid cells in inflammatory diseases : Clinical implications |
264 | c 2017-11-22 | |
264 | 1 | b Wiley,c 2018 |
520 | a Innate lymphoid cells (ILC) represent a group of lymphocytes that lack specific antigen receptors and are relatively rare as compared to adaptive lymphocytes. ILCs play important roles in allergic and nonallergic inflammatory diseases due to their location at barrier surfaces within the airways, gut, and skin, and they respond to cytokines produced by activated cells in their local environment. Innate lymphoid cells contribute to the immune response by the release of cytokines and other mediators, forming a link between innate and adaptive immunity. In recent years, these cells have been extensively characterized and their role in animal models of disease has been investigated. Data to translate the relevance of ILCs in human pathology, and the potential role of ILCs in diagnosis, as biomarkers and/or as future treatment targets are also emerging. This review, produced by a task force of the Immunology Section of the European Academy of Allergy and Clinical Immunology (EAACI), encompassing clinicians and researchers, highlights the role of ILCs in human allergic and nonallergic diseases in the airways, gastrointestinal tract, and skin, with a focus on new insights into clinical implications, therapeutic options, and future research opportunities. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
653 | a Allergy | |
653 | a Inflammatory diseases | |
653 | a Innate lymphoid cells | |
653 | a Therapeutic targets | |
700 | 1 | a Shikhagaie, M. M.u Academic Medical Center of University of Amsterdam (AMC)4 aut0 (Swepub:lu)med-mys |
700 | 1 | a Golebski, K.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Bernink, J. H.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Breynaert, C.u University Hospitals Leuven4 aut |
700 | 1 | a Creyns, B.u Catholic University of Leuven4 aut |
700 | 1 | a Diamant, Z.u Lund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,University Medical Center Groningen4 aut0 (Swepub:lu)med-zdt |
700 | 1 | a Fokkens, W. J.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Gevaert, P.u Ghent University4 aut |
700 | 1 | a Hellings, P.u University Hospitals Leuven4 aut |
700 | 1 | a Hendriks, R. W.4 aut |
700 | 1 | a Klimek, L.u Center for Rhinology and Allergology4 aut |
700 | 1 | a Mjösberg, J.u Karolinska Institutet,Karolinska Institute4 aut |
700 | 1 | a Morita, H.u National Center for Child Health and Development4 aut |
700 | 1 | a Ogg, G. S.u University of Oxford4 aut |
700 | 1 | a O'Mahony, L.u University of Zurich4 aut |
700 | 1 | a Schwarze, J.u University of Edinburgh4 aut |
700 | 1 | a Seys, S. F.u Catholic University of Leuven4 aut |
700 | 1 | a Shamji, M. H.u Imperial College London,MRC Human Nutrition Research4 aut |
700 | 1 | a Bal, S. M.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
710 | 2 | a Catholic University of Leuvenb Academic Medical Center of University of Amsterdam (AMC)4 org |
773 | 0 | t Allergy: European Journal of Allergy and Clinical Immunologyd : Wileyg 73:4, s. 837-850q 73:4<837-850x 0105-4538x 1398-9995 |
856 | 4 | u http://dx.doi.org/10.1111/all.13340y FULLTEXT |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.13340 |
856 | 4 8 | u https://lup.lub.lu.se/record/13298810-6eb4-4c19-86cb-1cb30a448886 |
856 | 4 8 | u https://doi.org/10.1111/all.13340 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:138023316 |
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