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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 05494naa a2201045 4500 | |
| 001 | oai:lup.lub.lu.se:169040a3-5233-492d-a890-7395026680ab | |
| 003 | SwePub | |
| 008 | 160401s2011 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:umu-49656 | |
| 024 | 7 | a https://lup.lub.lu.se/record/21606612 URI |
| 024 | 7 | a https://doi.org/10.1038/bjc.2011.2542 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-496562 URI |
| 040 | a (SwePub)lud (SwePub)umu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Key, T. J.4 aut |
| 245 | 1 0 | a Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies |
| 264 | c 2011-07-19 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2011 |
| 520 | a BACKGROUND: Breast cancer risk for postmenopausal women is positively associated with circulating concentrations of oestrogens and androgens, but the determinants of these hormones are not well understood. METHODS: Cross-sectional analyses of breast cancer risk factors and circulating hormone concentrations in more than 6000 postmenopausal women controls in 13 prospective studies. RESULTS: Concentrations of all hormones were lower in older than younger women, with the largest difference for dehydroepiandrosterone sulphate (DHEAS), whereas sex hormone-binding globulin (SHBG) was higher in the older women. Androgens were lower in women with bilateral ovariectomy than in naturally postmenopausal women, with the largest difference for free testosterone. All hormones were higher in obese than lean women, with the largest difference for free oestradiol, whereas SHBG was lower in obese women. Smokers of 15+ cigarettes per day had higher levels of all hormones than non-smokers, with the largest difference for testosterone. Drinkers of 20+ g alcohol per day had higher levels of all hormones, but lower SHBG, than non-drinkers, with the largest difference for DHEAS. Hormone concentrations were not strongly related to age at menarche, parity, age at first full-term pregnancy or family history of breast cancer. CONCLUSION: Sex hormone concentrations were strongly associated with several established or suspected risk factors for breast cancer, and may mediate the effects of these factors on breast cancer risk. British Journal of Cancer (2011) 105, 709-722. doi:10.1038/bjc.2011.254 www.bjcancer.com Published online 19 July 2011 (C) 2011 Cancer Research UK | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a breast cancer | |
| 653 | a hormones | |
| 653 | a oestrogens | |
| 653 | a androgens | |
| 653 | a sex hormone-binding | |
| 653 | a globulin | |
| 653 | a breast cancer | |
| 700 | 1 | a Appleby, P. N.4 aut |
| 700 | 1 | a Reeves, G. K.4 aut |
| 700 | 1 | a Roddam, A. W.4 aut |
| 700 | 1 | a Helzlsouer, K. J.4 aut |
| 700 | 1 | a Alberg, A. J.4 aut |
| 700 | 1 | a Rollison, D. E.4 aut |
| 700 | 1 | a Dorgan, J. F.4 aut |
| 700 | 1 | a Brinton, L. A.4 aut |
| 700 | 1 | a Overvad, K.4 aut |
| 700 | 1 | a Kaaks, R.4 aut |
| 700 | 1 | a Trichopoulou, A.4 aut |
| 700 | 1 | a Clavel-Chapelon, F.4 aut |
| 700 | 1 | a Panico, S.4 aut |
| 700 | 1 | a Duell, E. J.4 aut |
| 700 | 1 | a Peeters, P. H. M.4 aut |
| 700 | 1 | a Rinaldi, S.4 aut |
| 700 | 1 | a Riboli, E.4 aut |
| 700 | 1 | a Fentiman, I. S.4 aut |
| 700 | 1 | a Dowsett, M.4 aut |
| 700 | 1 | a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma |
| 700 | 1 | a Lenner, Peru Umeå universitet,Onkologi4 aut0 (Swepub:umu)pele0005 |
| 700 | 1 | a Hallmans, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
| 700 | 1 | a Baglietto, L.4 aut |
| 700 | 1 | a English, D. R.4 aut |
| 700 | 1 | a Giles, G. G.4 aut |
| 700 | 1 | a Hopper, J. L.4 aut |
| 700 | 1 | a Severi, G.4 aut |
| 700 | 1 | a Morris, H. A.4 aut |
| 700 | 1 | a Koenig, K.4 aut |
| 700 | 1 | a Zeleniuch-Jacquotte, A.4 aut |
| 700 | 1 | a Arslan, A. A.4 aut |
| 700 | 1 | a Toniolo, P.4 aut |
| 700 | 1 | a Shore, R. E.4 aut |
| 700 | 1 | a Krogh, V.4 aut |
| 700 | 1 | a Micheli, A.4 aut |
| 700 | 1 | a Berrino, F.4 aut |
| 700 | 1 | a Muti, P.4 aut |
| 700 | 1 | a Barrett-Connor, E.4 aut |
| 700 | 1 | a Laughlin, G. A.4 aut |
| 700 | 1 | a Kabuto, M.4 aut |
| 700 | 1 | a Akiba, S.4 aut |
| 700 | 1 | a Stevens, R. G.4 aut |
| 700 | 1 | a Neriishi, K.4 aut |
| 700 | 1 | a Land, C. E.4 aut |
| 700 | 1 | a Cauley, J. A.4 aut |
| 700 | 1 | a Lui, Li Yung4 aut |
| 700 | 1 | a Cummings, Steven R.4 aut |
| 700 | 1 | a Gunter, M. J.4 aut |
| 700 | 1 | a Rohan, T. E.4 aut |
| 700 | 1 | a Strickler, H. D.4 aut |
| 700 | 1 | a Hankinson, S E4 aut |
| 700 | 1 | a Tworoger, S S4 aut |
| 710 | 2 | a Kirurgib Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t British Journal of Cancerd : Springer Science and Business Media LLCg 105:5, s. 709-722q 105:5<709-722x 1532-1827x 0007-0920 |
| 856 | 4 | u http://dx.doi.org/10.1038/bjc.2011.254y FULLTEXT |
| 856 | 4 | u https://www.nature.com/articles/bjc2011254.pdf |
| 856 | 4 8 | u https://lup.lub.lu.se/record/2160661 |
| 856 | 4 8 | u https://doi.org/10.1038/bjc.2011.254 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-49656 |
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- Appleby, P. N.
- Reeves, G. K.
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- Rollison, D. E.
- Dorgan, J. F.
- Brinton, L. A.
- Overvad, K.
- Kaaks, R.
- Trichopoulou, A.
- Clavel-Chapelon, ...
- Panico, S.
- Duell, E. J.
- Peeters, P. H. M ...
- Rinaldi, S.
- Riboli, E.
- Fentiman, I. S.
- Dowsett, M.
- Manjer, Jonas
- Lenner, Per
- Hallmans, Göran
- Baglietto, L.
- English, D. R.
- Giles, G. G.
- Hopper, J. L.
- Severi, G.
- Morris, H. A.
- Koenig, K.
- Zeleniuch-Jacquo ...
- Arslan, A. A.
- Toniolo, P.
- Shore, R. E.
- Krogh, V.
- Micheli, A.
- Berrino, F.
- Muti, P.
- Barrett-Connor, ...
- Laughlin, G. A.
- Kabuto, M.
- Akiba, S.
- Stevens, R. G.
- Neriishi, K.
- Land, C. E.
- Cauley, J. A.
- Lui, Li Yung
- Cummings, Steven ...
- Gunter, M. J.
- Rohan, T. E.
- Strickler, H. D.
- Hankinson, S E
- Tworoger, S S
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