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  • D. Ubags, NikiUniversity of Lausanne (author)

ERS International Congress, Madrid, 2019: highlights from the Basic and translational Science Assembly

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020-03-02
  • European Respiratory Society (ERS),2020

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:18c2c8bc-0098-41fd-9041-c56dc3682833
  • https://lup.lub.lu.se/record/18c2c8bc-0098-41fd-9041-c56dc3682833URI
  • https://doi.org/10.1183/23120541.00350-2019DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • In this review, the Basic and Translational Sciences Assembly of the European Respiratory Society (ERS) provides an overview of the 2019 ERS International Congress highlights. In particular, we discuss how the novel and very promising technology of single cell sequencing has led to the development of a comprehensive map of the human lung, the lung cell atlas, including the discovery of novel cell types and new insights into cellular trajectories in lung health and disease. Further, we summarise recent insights in the field of respiratory infections, which can aid in a better understanding of the molecular mechanisms underlying these infections in order to develop novel vaccines and improved treatment options. Novel concepts delineating the early origins of lung disease are focused on the effects of pre- and post-natal exposures on neonatal lung development and long-term lung health. Moreover, we discuss how these early life exposures can affect the lung microbiome and respiratory infections. In addition, the importance of metabolomics and mitochondrial function analysis to subphenotype chronic lung disease patients according to their metabolic program is described. Finally, basic and translational respiratory science is rapidly moving forward and this will be beneficial for an advanced molecular understanding of the mechanisms underlying a variety of lung diseases. In the long-term this will aid in the development of novel therapeutic targeting strategies in the field of respiratory medicine.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Baker, JonathanImperial College London (author)
  • Boots, AgnesMaastricht University (author)
  • Costa, RitaGerman Center for Lung Research (DZL),Ludwig-Maximilian University of Munich (author)
  • El-Merhie, NataliaGerman Center for Lung Research (DZL),Forschungszentrum Borstel - Zentrum für Medizin und Biowissenschaften (author)
  • Fabre, AurelieUniversity College Dublin,St Vincent's University Hospital (author)
  • Faiz, AlenUniversity of Technology Sydney (author)
  • H. Heijink, IreneUniversity of Groningen (author)
  • S. Hiemstra, PieterLeiden University (author)
  • Lehmann, MareikeLudwig-Maximilian University of Munich,German Center for Lung Research (DZL) (author)
  • Meiners, SilkeGerman Center for Lung Research (DZL),Ludwig-Maximilian University of Munich (author)
  • Rolandsson Enes, SaraLund University,Lunds universitet,Lungbiologi,Forskargrupper vid Lunds universitet,Lung Biology,Lund University Research Groups,University of Vermont(Swepub:lu)med-sro (author)
  • Bartel, SabineUniversity of Groningen (author)
  • University of LausanneImperial College London (creator_code:org_t)

Related titles

  • In:ERJ Open Research: European Respiratory Society (ERS)6:12312-0541

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