Sökning: onr:"swepub:oai:lup.lub.lu.se:1f4adcac-f8fd-4864-ade4-14f7842b86ed" >
Matrix proteins: Po...
Matrix proteins: Potentials as body fluid markers of changes in the metabolism of cartilage and bone in arthritis
-
- Saxne, Tore (författare)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
-
- Heinegård, Dick (författare)
- Lund University,Lunds universitet
-
(creator_code:org_t)
- 1995
- 1995
- Engelska.
-
Ingår i: Journal of Rheumatology. - 0315-162X. ; 22 (suppl 43), s. 71-74
- Relaterad länk:
-
https://lup.lub.lu.s...
Abstract
Ämnesord
Stäng
- Altered dynamics of cartilage and bone matrix in joint diseases results in increased release of macromolecules into synovial fluid (SF). Such macromolecules are increasingly explored as potential markers of damage and severity. This report focuses on the possibilities of using quantification of tissue specific markers for grading the tissue lesion at the molecular level in arthritis. The theoretical and experimental rationale for such an approach is supported by the results in clinical studies. These studies indicate that simultaneous analysis of multiple cartilage and bone markers in the same SF or serum sample could be useful for defining degree of tissue involvement in rheumatoid arthritis and, possibly, in osteoarthritis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- Arthritis, Rheumatoid/metabolism
- Biomarkers/analysis
- Cartilage, Articular/metabolism
- Osteoarthritis/metabolism
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas