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Treatment of acute ...
Treatment of acute neonatal bacterial conjunctivitis: a comparison of fucidic acid to chloramphenicol eye drops
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Normann, EK (författare)
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Bakken, O (författare)
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Peltola, J (författare)
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- Andréasson, Bengt (författare)
- Lund University,Lunds universitet,Preventiv pediatrik,Forskargrupper vid Lunds universitet,Preventive Paediatrics,Lund University Research Groups
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Buhl, S (författare)
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Sigg, P (författare)
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Nielsen, K (författare)
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(creator_code:org_t)
- 2003-03-12
- 2002
- Engelska.
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Ingår i: Acta Ophthalmologica Scandinavica. - : Wiley. - 1395-3907. ; 80:2, s. 183-187
- Relaterad länk:
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http://dx.doi.org/10...
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https://onlinelibrar...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Purpose: To compare the clinical and bacteriological effects of fucidic acid (Fucithalmic(R): 1.0%) and chloramphenicol (Minims(R): 0.5%) eye drops in neonates with a clinical diagnosis of acute conjunctivitis of suspected bacterial origin. Methods: A total of 456 newborns with gestational age > 32 weeks with acute conjunctivitis of suspected bacterial origin acquired within the first 28 days of life were included in the study. They were randomly assigned to a 7-day treatment with eye drops using either fucidic acid (1.0%) (Fucithalmic(R)) applied or chloramphenicol (0.5%) (Minims(R) Chloramphenicol) applied twice per day six times per day. The subjects were followed up with two visits (on days 1 and 8) and by telephone 2 weeks after the end of treatment. Results: Eighty-nine per cent of the neonates treated with Fucithalmic(R) were cured, compared to 87.9% of those treated with Minims(R) Chloramphenicol (n.s). The drug was used as instructed in 90.7% of patients treated with Fucithalmic(R) and in 78.0% of those treated with Minims(R) Chloramphenicol (P < 0.001). Conclusion: Treating neonatal conjunctivitis with fucidic acid is easier than with chloramphenicol and is equally effective.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Nyckelord
- fucidic acid
- conjunctivitis
- neonatal
- chloramphenicol
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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