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Morbidity and Outco...
Morbidity and Outcomes After Distal Pancreatectomy for Primary Retroperitoneal Sarcoma : An Analysis by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group
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- Bagaria, Sanjay P. (författare)
- Mayo Clinic Florida
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- Swallow, Carol (författare)
- Princess Margaret Hospital University of Toronto
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- Suraweera, Harini (författare)
- Princess Margaret Hospital University of Toronto
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- Raut, Chandrajit P. (författare)
- Brigham and Women's Hospital / Harvard Medical School
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- Fairweather, Mark (författare)
- Brigham and Women's Hospital / Harvard Medical School
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- Cananzi, Ferdinando (författare)
- Humanitas Research Hospital,Humanitas University
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- Quagliuolo, Vittorio (författare)
- Humanitas Research Hospital,Humanitas University
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- Grignani, Giovanni (författare)
- Institute for Cancer Research and Treatment, Candiolo
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- Hompes, Daphne (författare)
- University Hospitals Leuven
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- Ford, Samuel J. (författare)
- University Hospitals Birmingham
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- Nessim, Carolyn (författare)
- University of Ottawa
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- Apte, Sameer (författare)
- University of Ottawa
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- Skoczylas, Jacek (författare)
- The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
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- Rutkowski, Piotr (författare)
- The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
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- Bonvalot, Sylvie (författare)
- Curie Institute, Paris
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- Tzanis, Dimitri (författare)
- Curie Institute, Paris
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- Gabriel, Emmanuel (författare)
- Mayo Clinic Florida
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- Pennacchioli, Elisabetta (författare)
- European Institute of Oncology
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- Albertsmeier, Markus (författare)
- Ludwig-Maximilian University of Munich
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- Canter, Robert J. (författare)
- University of California, Davis
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- Pollock, Raphael (författare)
- Ohio State University
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- Grignol, Valerie (författare)
- Ohio State University
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- Cardona, Kenneth (författare)
- Emory University
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- Gamboa, Adriana C. (författare)
- Emory University
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- Novak, Marko (författare)
- Institute of Oncology, Ljubljana
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- Stoeckle, Eberhard (författare)
- Institut Bergoníe
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- Almquist, Martin (författare)
- Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Endokrin- och sarkomkirurgi,Forskargrupper vid Lunds universitet,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Endocrine and Sarcoma Surgery,Lund University Research Groups,Skåne University Hospital
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- Ahuja, Nita (författare)
- Yale University
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- Klemen, Nicholas (författare)
- Yale University
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- Van Houdt, Winan (författare)
- Antoni Van Leeuwenhoek Hospital
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- Gyorki, David (författare)
- Cedars-Sinai Medical Center
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- Gangi, Alexandra (författare)
- Peter MacCallum Cancer Centre
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- Rastrelli, Marco (författare)
- Veneto Institute of Oncology
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- van der Hage, Jos (författare)
- Leiden University Medical Centre
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- Schrage, Yvonne (författare)
- Leiden University Medical Centre
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Valeri, Sergio (författare)
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- Conti, Lorenzo (författare)
- Istituto Nazionale dei Tumori
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- Spiegel, Matthew R. (författare)
- Mayo Clinic Florida
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- Li, Zhou (författare)
- Mayo Clinic Florida
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- Fiore, Marco (författare)
- Istituto Nazionale dei Tumori
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- Gronchi, Alessandro (författare)
- Istituto Nazionale dei Tumori
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(creator_code:org_t)
- 2021-03-19
- 2021
- Engelska 8 s.
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Ingår i: Annals of Surgical Oncology. - : Springer Science and Business Media LLC. - 1068-9265 .- 1534-4681. ; 28:11, s. 6882-6889
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Multi-visceral resection often is used in the treatment of retroperitoneal sarcoma (RPS). The morbidity after distal pancreatectomy for primary pancreatic cancer is well-documented, but the outcomes after distal pancreatectomy for primary RPS are not. This study aimed to evaluate morbidity and oncologic outcomes after distal pancreatectomy for primary RPS. Methods: In this study, 26 sarcoma centers that are members of the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) retrospectively identified consecutive patients who underwent distal pancreatectomy for primary RPS from 2008 to 2017. The outcomes measured were 90-day severe complications (Clavien-Dindo ≥ 3), postoperative pancreatic fistula (POPF) rate, and oncologic outcomes. Results: Between 2008 and 2017, 280 patients underwent distal pancreatectomy for primary RPS. The median tumor size was 25 cm, and the median number of organs resected, including the pancreas, was three. In 96% of the operations, R0/R1 resection was achieved. The 90-day severe complication rate was 40 %. The grades B and C POPF complication rates were respectively 19% and 5% and not associated with worse overall survival. Administration of preoperative radiation and factors to mitigate POPF did not have an impact on the risk for the development of a POPF. The RPS invaded the pancreas in 38% of the patients, and local recurrence was doubled for the patients who had a microscopic, positive pancreas margin (hazard ratio, 2.0; p = 0.042). Conclusion: Distal pancreatectomy for primary RPS has acceptable morbidity and oncologic outcomes and is a reasonable approach to facilitate complete tumor resection.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
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Bagaria, Sanjay ...
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Swallow, Carol
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Suraweera, Harin ...
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Raut, Chandrajit ...
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Fairweather, Mar ...
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Cananzi, Ferdina ...
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Quagliuolo, Vitt ...
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Grignani, Giovan ...
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Hompes, Daphne
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Ford, Samuel J.
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Nessim, Carolyn
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Apte, Sameer
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Skoczylas, Jacek
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Rutkowski, Piotr
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Bonvalot, Sylvie
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Tzanis, Dimitri
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Gabriel, Emmanue ...
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Pennacchioli, El ...
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Albertsmeier, Ma ...
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Canter, Robert J ...
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Pollock, Raphael
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Grignol, Valerie
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Cardona, Kenneth
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Gamboa, Adriana ...
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Novak, Marko
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Stoeckle, Eberha ...
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Almquist, Martin
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Ahuja, Nita
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Klemen, Nicholas
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Van Houdt, Winan
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Gyorki, David
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Gangi, Alexandra
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Rastrelli, Marco
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van der Hage, Jo ...
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Schrage, Yvonne
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Valeri, Sergio
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Conti, Lorenzo
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Spiegel, Matthew ...
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Li, Zhou
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Fiore, Marco
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Gronchi, Alessan ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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Annals of Surgic ...
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Lunds universitet