Sökning: onr:"swepub:oai:lup.lub.lu.se:3ac53ce5-5f4e-4815-8c37-252b6bb7ec2f" > MVnet : automated t...
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000 | 06451naa a2200469 4500 | |
001 | oai:lup.lub.lu.se:3ac53ce5-5f4e-4815-8c37-252b6bb7ec2f | |
003 | SwePub | |
008 | 221021s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/3ac53ce5-5f4e-4815-8c37-252b6bb7ec2f2 URI |
024 | 7 | a https://doi.org/10.1186/s12968-021-00824-22 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Gonzales, Ricardo A.u Lund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Yale University,Universidad de Ingeniería y Tecnología (UTEC)4 aut0 (Swepub:lu)ri2341go |
245 | 1 0 | a MVnet : automated time-resolved tracking of the mitral valve plane in CMR long-axis cine images with residual neural networks: a multi-center, multi-vendor study |
264 | c 2021-12-02 | |
264 | 1 | b Springer Science and Business Media LLC,c 2021 |
520 | a Background: Mitral annular plane systolic excursion (MAPSE) and left ventricular (LV) early diastolic velocity (e’) are key metrics of systolic and diastolic function, but not often measured by cardiovascular magnetic resonance (CMR). Its derivation is possible with manual, precise annotation of the mitral valve (MV) insertion points along the cardiac cycle in both two and four-chamber long-axis cines, but this process is highly time-consuming, laborious, and prone to errors. A fully automated, consistent, fast, and accurate method for MV plane tracking is lacking. In this study, we propose MVnet, a deep learning approach for MV point localization and tracking capable of deriving such clinical metrics comparable to human expert-level performance, and validated it in a multi-vendor, multi-center clinical population. Methods: The proposed pipeline first performs a coarse MV point annotation in a given cine accurately enough to apply an automated linear transformation task, which standardizes the size, cropping, resolution, and heart orientation, and second, tracks the MV points with high accuracy. The model was trained and evaluated on 38,854 cine images from 703 patients with diverse cardiovascular conditions, scanned on equipment from 3 main vendors, 16 centers, and 7 countries, and manually annotated by 10 observers. Agreement was assessed by the intra-class correlation coefficient (ICC) for both clinical metrics and by the distance error in the MV plane displacement. For inter-observer variability analysis, an additional pair of observers performed manual annotations in a randomly chosen set of 50 patients. Results: MVnet achieved a fast segmentation (<1 s/cine) with excellent ICCs of 0.94 (MAPSE) and 0.93 (LV e’) and a MV plane tracking error of −0.10 ± 0.97 mm. In a similar manner, the inter-observer variability analysis yielded ICCs of 0.95 and 0.89 and a tracking error of −0.15 ± 1.18 mm, respectively. Conclusion: A dual-stage deep learning approach for automated annotation of MV points for systolic and diastolic evaluation in CMR long-axis cine images was developed. The method is able to carefully track these points with high accuracy and in a timely manner. This will improve the feasibility of CMR methods which rely on valve tracking and increase their utility in a clinical setting. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
653 | a Annotation | |
653 | a Left ventricular dysfunction | |
653 | a Residual neural networks | |
700 | 1 | a Seemann, Feliciau Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Yale University4 aut0 (Swepub:lu)med-fse |
700 | 1 | a Lamy, Jérômeu Yale University4 aut |
700 | 1 | a Mojibian, Hamidu Yale University4 aut |
700 | 1 | a Atar, Danu Oslo university hospital4 aut |
700 | 1 | a Erlinge, Davidu Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kard-der |
700 | 1 | a Steding-Ehrenborg, Katarinau Lund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-kns |
700 | 1 | a Arheden, Håkanu Lund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)klfy-har |
700 | 1 | a Hu, Chenxiu Shanghai Jiao Tong University4 aut |
700 | 1 | a Onofrey, John A.u Yale University4 aut |
700 | 1 | a Peters, Dana C.u Yale University4 aut |
700 | 1 | a Heiberg, Einaru Lund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,LTH profilområde: Teknik för hälsa,LTH profilområden,Lunds Tekniska Högskola,Lund Cardiac MR Group,Lund University Research Groups,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine,LTH Profile Area: Engineering Health,LTH Profile areas,Faculty of Engineering, LTH,Skåne University Hospital4 aut0 (Swepub:lu)klin-eh0 |
710 | 2 | a Klinisk fysiologi, Lundb Sektion V4 org |
773 | 0 | t Journal of Cardiovascular Magnetic Resonanced : Springer Science and Business Media LLCg 23, s. 1-15q 23<1-15x 1097-6647x 1532-429X |
856 | 4 | u http://dx.doi.org/10.1186/s12968-021-00824-2x freey FULLTEXT |
856 | 4 | u https://jcmr-online.biomedcentral.com/track/pdf/10.1186/s12968-021-00824-2 |
856 | 4 8 | u https://lup.lub.lu.se/record/3ac53ce5-5f4e-4815-8c37-252b6bb7ec2f |
856 | 4 8 | u https://doi.org/10.1186/s12968-021-00824-2 |
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