SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:lup.lub.lu.se:3f6fb678-4eab-4300-b1c0-f9ebc213b420"
 

Sökning: onr:"swepub:oai:lup.lub.lu.se:3f6fb678-4eab-4300-b1c0-f9ebc213b420" > The REal Life EVide...

  • Campbell, Jonathan D.University of Colorado (författare)

The REal Life EVidence AssessmeNt Tool (RELEVANT) : Development of a novel quality assurance asset to rate observational comparative effectiveness research studies

  • Artikel/kapitelEngelska2019

Förlag, utgivningsår, omfång ...

  • 2019-03-27
  • Wiley,2019

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:3f6fb678-4eab-4300-b1c0-f9ebc213b420
  • https://lup.lub.lu.se/record/3f6fb678-4eab-4300-b1c0-f9ebc213b420URI
  • https://doi.org/10.1186/s13601-019-0256-9DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Background: Evidence from observational comparative effectiveness research (CER) is ranked below that from randomized controlled trials in traditional evidence hierarchies. However, asthma observational CER studies represent an important complementary evidence source answering different research questions and are particularly valuable in guiding clinical decision making in real-life patient and practice settings. Tools are required to assist in quality appraisal of observational CER to enable identification of and confidence in high-quality CER evidence to inform guideline development. Methods: The REal Life EVidence AssessmeNt Tool (RELEVANT) was developed through a step-wise approach. We conducted an iterative refinement of the tool based on Task Force member expertise and feedback from pilot testing the tool until reaching adequate inter-rater agreement percentages. Two distinct pilots were conducted - the first involving six members of the Respiratory Effectiveness Group (REG) and European Academy of Allergy and Clinical Immunology (EAACI) joint Task Force for quality appraisal of observational asthma CER; the second involving 22 members of REG and EAACI membership. The final tool consists of 21 quality sub-items distributed across seven methodology domains: Background, Design, Measures, Analysis, Results, Discussion/Interpretation, and Conflict of Interest. Eleven of these sub-items are considered critical and named "primary sub-items". Results: Following the second pilot, RELEVANT showed inter-rater agreement ≥ 70% for 94% of all primary and 93% for all secondary sub-items tested across three rater groups. For observational CER to be classified as sufficiently high quality for future guideline consideration, all RELEVANT primary sub-items must be fulfilled. The ten secondary sub-items further qualify the relative strengths and weaknesses of the published CER evidence. RELEVANT could also be applicable to general quality appraisal of observational CER across other medical specialties. Conclusions: RELEVANT is the first quality checklist to assist in the appraisal of published observational CER developed through iterative feedback derived from pilot implementation and inter-rater agreement evaluation. Developed for a REG-EAACI Task Force quality appraisal of recent asthma CER, RELEVANT also has wider utility to support appraisal of CER literature in general (including pre-publication). It may also assist in manuscript development and in educating relevant stakeholders about key quality markers in observational CER.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Perry, RobertUniversity of Colorado (författare)
  • Papadopoulos, Nikolaos G.National and Kapodistrian University of Athens,University of Manchester (författare)
  • Krishnan, JerryUniversity of Illinois at Chicago (författare)
  • Brusselle, GuyGhent University Hospital,Erasmus University Medical Center (författare)
  • Chisholm, AlisonRespiratory Effectiveness Group (författare)
  • Bjermer, LeifLund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)lung-lbj (författare)
  • Thomas, MichaelUniversity of Southampton (författare)
  • Van Ganse, EricUniversity of Lyon (författare)
  • Van Den Berge, MaartenUniversity of Groningen,University Medical Center Groningen (författare)
  • Quint, JenniferImperial College London (författare)
  • Price, DavidUniversity of Aberdeen,Observational and Pragmatic Research Institute Pte Ltd (författare)
  • Roche, NicolasParis Descartes University,Cochin Hospital (författare)
  • University of ColoradoNational and Kapodistrian University of Athens (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Clinical and Translational Allergy: Wiley9:12045-7022

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy