Sökning: onr:"swepub:oai:lup.lub.lu.se:44513f7b-2ec2-40d6-8ec0-514890aa1305" > Hepatopancreatoduod...
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000 | 06258naa a2200829 4500 | |
001 | oai:lup.lub.lu.se:44513f7b-2ec2-40d6-8ec0-514890aa1305 | |
003 | SwePub | |
008 | 200117s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:144837311 | |
024 | 7 | a https://lup.lub.lu.se/record/44513f7b-2ec2-40d6-8ec0-514890aa13052 URI |
024 | 7 | a https://doi.org/10.1016/j.hpb.2019.12.0082 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1448373112 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a D'Souza, Melroy A.u Karolinska Institutet4 aut |
245 | 1 0 | a Hepatopancreatoduodenectomy –a controversial treatment for bile duct and gallbladder cancer from a European perspective |
264 | 1 | b Elsevier BV,c 2020 |
300 | a 10 s. | |
520 | a Background: Hepatopancreatoduodenectomy (HPD) is an aggressive operation for treatment of advanced bile duct and gallbladder cancer associated with high perioperative morbidity and mortality, and uncertain oncological benefit in terms of survival. Few reports on HPD from Western centers exist. The purpose of this study was to evaluate safety and efficacy for HPD in European centers. Method: Members of the European-African HepatoPancreatoBiliary Association were invited to report all consecutive patients operated with HPD for bile duct or gallbladder cancer between January 2003 and January 2018. The patient and tumor characteristics, perioperative and survival outcomes were analyzed. Results: In total, 66 patients from 19 European centers were included in the analysis. 90-day mortality rate was 17% and 13% for bile duct and gallbladder cancer respectively. All factors predictive of perioperative mortality were patient and disease-specific. The three-year overall survival excluding 90-day mortality was 80% for bile duct and 30% for gallbladder cancer (P = 0.013). In multivariable analysis R0-resection had a significant impact on overall survival. Conclusion: HPD, although being associated with substantial perioperative mortality, can offer a survival benefit in patient subgroups with bile duct cancer and gallbladder cancer. To achieve negative resection margins is paramount for an improved survival outcome. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
700 | 1 | a Valdimarsson, Valentinus T.u Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)va4706va |
700 | 1 | a Campagnaro, Tommasou University Hospital Verona4 aut |
700 | 1 | a Cauchy, Francoisu Beaujon Hospital4 aut |
700 | 1 | a Chatzizacharias, Nikolaos A.u New Queen Elizabeth Hospital4 aut |
700 | 1 | a D'Hondt, Mathieu4 aut |
700 | 1 | a Dasari, Bobbyu New Queen Elizabeth Hospital4 aut |
700 | 1 | a Ferrero, Alessandrou Mauriziano Hospital, Turin4 aut |
700 | 1 | a Franken, Lotte C.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Fusai, Giuseppeu Great Ormond Street Hospital4 aut |
700 | 1 | a Guglielmi, Alfredou University Hospital Verona4 aut |
700 | 1 | a Hagendoorn, Jeroenu University Medical Center Utrecht4 aut |
700 | 1 | a Hidalgo Salinas, Camilau Great Ormond Street Hospital4 aut |
700 | 1 | a Hoogwater, Frederik J.H.u University Medical Center Groningen4 aut |
700 | 1 | a Jorba, Rosau Hospital Joan XXIII4 aut |
700 | 1 | a Karanjia, Nariman4 aut |
700 | 1 | a Knoefel, Wolfram T.u University Hospital of Düsseldorf4 aut |
700 | 1 | a Kron, Philippu Leeds Teaching Hospitals NHS Trust4 aut |
700 | 1 | a Lahiri, Rajiv4 aut |
700 | 1 | a Langella, Serenau Mauriziano Hospital, Turin4 aut |
700 | 1 | a Le Roy, Bertrandu Beaujon Hospital4 aut |
700 | 1 | a Lehwald-Tywuschik, Nadjau University Hospital of Düsseldorf4 aut |
700 | 1 | a Lesurtel, Mickaelu Claude Bernard University Lyon 14 aut |
700 | 1 | a Li, Junu University Medical Center Hamburg-Eppendorf4 aut |
700 | 1 | a Lodge, J. Peter A.u Leeds Teaching Hospitals NHS Trust4 aut |
700 | 1 | a Martinou, Erini4 aut |
700 | 1 | a Molenaar, Izaak Q.u University Medical Center Utrecht4 aut |
700 | 1 | a Nikov, Andreju The Military University Hospital Prague4 aut |
700 | 1 | a Poves, Ignasiu Hospital del Mar Medical Research Institute4 aut |
700 | 1 | a Rassam, Fadiu Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Russolillo, Nadiau Mauriziano Hospital, Turin4 aut |
700 | 1 | a Soubrane, Olivieru Beaujon Hospital4 aut |
700 | 1 | a Stättner, Stefanu Medical University of Innsbruck4 aut |
700 | 1 | a van Dam, Ronald M.u Yukioka Hospital4 aut |
700 | 1 | a van Gulik, Thomas M.u Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Serrablo, Alejandrou Miguel Servet University Hospital4 aut |
700 | 1 | a Gallagher, Tom M.u St Vincent's University Hospital4 aut |
700 | 1 | a Sturesson, Christianu Karolinska Institutet4 aut0 (Swepub:lu)med-cst |
710 | 2 | a Karolinska Institutetb Kirurgi, Lund4 org |
710 | 2 | a E-AHPBA scientific and research committee |
773 | 0 | t HPBd : Elsevier BVg 22:9, s. 1339-1348q 22:9<1339-1348x 1365-182X |
773 | 0 | t HPB : the official journal of the International Hepato Pancreato Biliary Associationd : Elsevier BVg 22:9, s. 1339-1348q 22:9<1339-1348x 1477-2574 |
856 | 4 | u http://dx.doi.org/10.1016/j.hpb.2019.12.008y FULLTEXT |
856 | 4 | u http://www.hpbonline.org/article/S1365182X19332241/pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/44513f7b-2ec2-40d6-8ec0-514890aa1305 |
856 | 4 8 | u https://doi.org/10.1016/j.hpb.2019.12.008 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:144837311 |
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