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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04054naa a2200337 4500 | |
| 001 | oai:lup.lub.lu.se:468f7330-92d7-4b10-b087-ee7ba7ac57fe | |
| 003 | SwePub | |
| 008 | 160504s2016 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/468f7330-92d7-4b10-b087-ee7ba7ac57fe2 URI |
| 024 | 7 | a https://doi.org/10.1186/s40064-016-1953-72 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Ignell, Claesu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Helsingborg Hospital4 aut0 (Swepub:lu)med-cai |
| 245 | 1 0 | a Model for individual prediction of diabetes up to 5 years after gestational diabetes mellitus |
| 264 | c 2016-03-11 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2016 |
| 520 | a AIMS: To identify predictors of diabetes development up to 5 years after gestational diabetes mellitus (GDM) and to develop a prediction model for individual use.METHODS: Five years after GDM, a 75-g oral glucose tolerance test (OGTT) was performed in 362 women, excluding women already diagnosed with diabetes at 1- to 2-year follow-up or later (n = 45). All but 21 women had results from follow-up at 1-2 years, while 84 women were lost from that point. Predictive variables were identified by logistic regression analysis.RESULTS: Five years after GDM, 28/362 women (8 %) were diagnosed with diabetes whereas 187/362 (52 %) had normal glucose tolerance (NGT). Of the latter, 139/187 (74 %) also had NGT at 1- to 2-year follow-up. In simple regression analysis, using NGT at 1-2 years and at 5 years as the reference, diabetes at 1- to 2-year follow-up or later was clearly associated with easily assessable clinical variables, such as BMI at 1- to 2-year follow-up, 2-h OGTT glucose concentration during pregnancy, and non-European origin (P < 0.0001). A prediction model based on these variables resulting in 86 % correct classifications, with an area under the receiver-operating characteristic curve of 0.91 (95 % CI 0.86-0.95), was applied in a function-sheet line diagram illustrating the individual effect of weight on diabetes risk.CONCLUSIONS: The results highlight the importance of BMI as a potentially modifiable risk factor for diabetes after GDM. Our proposed prediction model performed well, and should encourage validation in other populations in future studies. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
| 700 | 1 | a Ekelund, Magnusu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Helsingborg Hospital4 aut0 (Swepub:lu)med-meu |
| 700 | 1 | a Anderberg, Evau Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)gyn-ean |
| 700 | 1 | a Berntorp, Kerstinu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-kbe |
| 710 | 2 | a Genomik, diabetes och endokrinologib Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t SpringerPlusd : Springer Science and Business Media LLCg 5q 5x 2193-1801 |
| 856 | 4 | u http://dx.doi.org/10.1186/s40064-016-1953-7x freey FULLTEXT |
| 856 | 4 | u https://springerplus.springeropen.com/track/pdf/10.1186/s40064-016-1953-7 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/468f7330-92d7-4b10-b087-ee7ba7ac57fe |
| 856 | 4 8 | u https://doi.org/10.1186/s40064-016-1953-7 |
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