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A randomised controlled trial of integrated psychological therapy for traumatic stress and substance use among adolescents: Trial protocol
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- Mills, Katherine (författare)
- University of Sydney
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- Barrett, Emma (författare)
- University of Sydney
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- Back, Sudie (författare)
- Medical University of South Carolina
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- (creator_code:org_t)
- 2020-11-30
- 2020
- Engelska.
- Ingår i: BMJ Open. - : BMJ. - 2044-6055. ; 10
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- Introduction: Post-traumatic stress disorder (PTSD) and substance use disorder frequently co-occur and tend to have their onset during adolescence. Although research has highlighted the importance of treating these disorders in an integrated fashion, there is a dearth of empirically validated integrated treatment options for adolescents with this comorbidity. This paper describes the study protocol for a randomised controlled trial (RCT) examining the efficacy of an integrated trauma-focused cognitive–behavioural treatment for traumatic stress and substance use among adolescents (Concurrent Treatment of PTSD and Substance Use Using Prolonged Exposure - Adolescent (COPE-A)), relative to a supportive counselling control condition (Person-Centred Therapy (PCT)). Methods and analysis: A two-arm, parallel, single-blind RCT with blinded follow-up at 4 and 12 months poststudy entry will be conducted in Sydney, Australia. Participants (n~100 adolescents aged 12–18 years) and their caregivers (caregiver participation is optional) will be allocated to undergo either COPE-A or PCT (allocation ratio 1:1) using minimisation. Both therapies will be delivered individually by project psychologists over a maximum of 16 sessions of 60–90 min duration and will include provision of up to four 30 min optional caregiver sessions. The primary outcome will be between-group differences in change in the severity of PTSD symptoms from baseline to 4-month follow-up, as measured by the Clinician-Administered PTSD Scale for Children and Adolescents for DSM-5. Ethics and dissemination: Ethical approval has been obtained from the human research ethics committees of the Sydney Children’s Hospital Network (HREC/17/SCHN/306) and the University of Sydney (HREC 2018/863). Findings will be published in peer-reviewed journals and presented at scientific conferences. Trial registration number: ACTRN12618000785202; Pre-reults.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- PTSD
- Substance use disorders
- Children and Adolescents
- Randomized Controlled Trial
- CBT
- Integrated Treatment
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- Mills, Katherine
- Barrett, Emma
- Back, Sudie
- Cobham, Vanessa
- Bendall, Sarah
- Perrin, Sean
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- Brady, Kathleen
- Ross, Joanne
- Peach, Natalie
- Kihas, Ivana
- Cassar, Joanne
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- Teesson, Maree
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