onr:"swepub:oai:lup.lub.lu.se:59e6632b-d362-4342-9748-295562a35cd7"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04457naa a2200517 4500 | |
| 001 | oai:lup.lub.lu.se:59e6632b-d362-4342-9748-295562a35cd7 | |
| 003 | SwePub | |
| 008 | 191205s2019 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-397705 | |
| 009 | oai:prod.swepub.kib.ki.se:142217078 | |
| 024 | 7 | a https://lup.lub.lu.se/record/59e6632b-d362-4342-9748-295562a35cd72 URI |
| 024 | 7 | a https://doi.org/10.1111/bjh.163172 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3977052 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1422170782 URI |
| 040 | a (SwePub)lud (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Glimelius, Ingrid,d 1975-u Karolinska Institutet,Uppsala universitet,Karolinska Institute,Department of Medicine, Division of Clinical Epidemiology, Karolinska Institutet and Karolinska University Hospital,Uppsala University Hospital,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)inggl846 |
| 245 | 1 0 | a Comorbidities and sex differences in causes of death among mantle cell lymphoma patients – A nationwide population-based cohort study |
| 264 | c 2019-11-13 | |
| 264 | 1 | b Wiley,c 2019 |
| 520 | a The prognosis for mantle cell lymphoma (MCL) remains poor. Our aim was to assess the impact of comorbidities on survival and causes of death. For 1,385 MCL patients (1,009 males, 376 females) diagnosed in 2000–2014 (median age 71 years, range 22–96) comorbidities ≤ 10 years of diagnosis were classified according to the Charlson comorbidity index (CCI; 0, 1, 2+). Hazard ratios (HRs) with 95% confidence intervals (CIs) were estimated to compare lymphoma-specific and all-cause mortality rates. Model-based predictions were used to obtain probabilities of death. Overall, 44% had any comorbidity (CCI 1+) and 28% severe comorbidity (CCI 2+). Over a median follow-up of 3·7 years (range 0–16), 633 (46%) died, the majority (76%) from lymphoma. Severe comorbidity was independently associated with higher all-cause [hazard ratio (HR) = 1·52; 95% CI: 1·24–1·85) and lymphoma-specific mortality (HR = 1·31; 95% CI: 1·04–1·65). Particularly among patients with connective tissue, renal and psychiatric diseases, and dementia. Among females with any comorbidity, non-lymphoma deaths represented a larger proportion of all deaths, compared to males with any comorbidity. In general, more efficient lymphoma treatments need to be considered also for patients with severe comorbidity. However, among females with any comorbidity, the likelihood of non-lymphoma death was still considerable, perhaps favouring a more liberal use of a “wait and watch” approach. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a cause of death | |
| 653 | a comorbidity | |
| 653 | a lymphoma-specific mortality | |
| 653 | a mantle cell lymphoma | |
| 653 | a sex | |
| 653 | a cause of death | |
| 700 | 1 | a Smedby, Karin E.u Karolinska Institutet,Karolinska Institute,Karolinska University Hospital4 aut |
| 700 | 1 | a Eloranta, Sandrau Karolinska Institute,Karolinska University Hospital4 aut |
| 700 | 1 | a Jerkeman, Matsu Lund University,Lunds universitet,Skåne University Hospital4 aut0 (Swepub:lu)onk-mje |
| 700 | 1 | a Weibull, Caroline E.u Karolinska Institutet,Karolinska Institute,Karolinska University Hospital4 aut |
| 710 | 2 | a Karolinska Instituteb Department of Medicine, Division of Clinical Epidemiology, Karolinska Institutet and Karolinska University Hospital4 org |
| 773 | 0 | t British Journal of Haematologyd : Wileyx 0007-1048x 1365-2141 |
| 856 | 4 | u http://dx.doi.org/10.1111/bjh.16317y FULLTEXT |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.16317 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/59e6632b-d362-4342-9748-295562a35cd7 |
| 856 | 4 8 | u https://doi.org/10.1111/bjh.16317 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397705 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:142217078 |
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