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First-year mortalit...
First-year mortality in incident dialysis patients : results of the Peridialysis study
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- Heaf, James (författare)
- Zealand University Hospital
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- Heiro, Maija (författare)
- Turku University Hospital
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- Petersons, Aivars (författare)
- Paula Stradina Clinical University Hospital
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visa fler...
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- Vernere, Baiba (författare)
- Paula Stradina Clinical University Hospital
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- Povlsen, Johan V (författare)
- Aarhus University Hospital
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- Sørensen, Anette Bagger (författare)
- Aarhus University Hospital
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- Clyne, Naomi (författare)
- Lund University,Lunds universitet,Kliniska studier vid kronisk njursjukdom (CKD),Forskargrupper vid Lunds universitet,Clinical studies in CKD,Lund University Research Groups,Skåne University Hospital
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- Bumblyte, Inga (författare)
- Lithuanian University of Health Sciences
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- Zilinskiene, Alanta (författare)
- Lithuanian University of Health Sciences
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- Randers, Else (författare)
- Viborg Regional Hospital
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- Løkkegaard, Niels (författare)
- Holbæk Hospital
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- Rosenberg, Mai (författare)
- University of Tartu,Tartu University Hospital
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- Kjellevold, Stig (författare)
- Vestfold Hospital
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- Kampmann, Jan Dominik (författare)
- Hospital of Southern Jutland
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- Rogland, Björn (författare)
- Central Hospital Kristianstad
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- Lagreid, Inger (författare)
- St. Olav’s University Hospital
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- Heimburger, Olof (författare)
- Karolinska Institutet,Karolinska Institute
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- Qureshi, Abdul Rashid (författare)
- Karolinska Institutet,Karolinska Institute
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- Lindholm, Bengt (författare)
- Karolinska Institutet,Karolinska Institute
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(creator_code:org_t)
- 2022-06-27
- 2022
- Engelska.
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Ingår i: BMC Nephrology. - : Springer Science and Business Media LLC. - 1471-2369. ; 23:1
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Controversy surrounds which factors are important for predicting early mortality after dialysis initiation (DI). We investigated associations of predialysis course and circumstances affecting planning and execution of DI with mortality following DI.METHODS: Among 1580 patients participating in the Peridialysis study, a study of causes and timing of DI, we registered features of predialysis course, clinical and biochemical data at DI, incidence of unplanned suboptimal DI, contraindications to peritoneal dialysis (PD) or hemodialysis (HD), and modality preference, actual choice, and cause of modality choice. Patients were followed for 12 months or until transplantation. A flexible parametric model was used to identify independent factors associated with all-cause mortality.RESULTS: First-year mortality was 19.33%. Independent factors predicting death were high age, comorbidity, clinical contraindications to PD or HD, suboptimal DI, high eGFR, low serum albumin, hyperphosphatemia, high C-reactive protein, signs of overhydration and cerebral symptoms at DI. Among 1061 (67.2%) patients who could select dialysis modality based on personal choice, 654 (61.6%) chose PD, 368 (34.7%) center HD and 39 (3.7%) home HD. The 12-months survival did not differ significantly between patients receiving PD and in-center HD.CONCLUSIONS: First-year mortality in incident dialysis patients was in addition to high age and comorbidity, associated with clinical contraindications to PD or HD, clinical symptoms, hyperphosphatemia, inflammation, and suboptimal DI. In patients with a "free" choice of dialysis modality based on their personal preferences, PD and in-center HD led to broadly similar short-term outcomes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Humans
- Hyperphosphatemia/etiology
- Incidence
- Kidney Failure, Chronic
- Peritoneal Dialysis/adverse effects
- Renal Dialysis/methods
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Heaf, James
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Heiro, Maija
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Petersons, Aivar ...
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Vernere, Baiba
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Povlsen, Johan V
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Sørensen, Anette ...
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visa fler...
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Clyne, Naomi
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Bumblyte, Inga
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Zilinskiene, Ala ...
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Randers, Else
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Løkkegaard, Niel ...
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Rosenberg, Mai
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Kjellevold, Stig
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Kampmann, Jan Do ...
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Rogland, Björn
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Lagreid, Inger
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Heimburger, Olof
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Qureshi, Abdul R ...
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Lindholm, Bengt
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
- Artiklar i publikationen
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BMC Nephrology
- Av lärosätet
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Lunds universitet
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Karolinska Institutet