onr:"swepub:oai:lup.lub.lu.se:6e061dc0-17a5-4a8e-b176-2731b26027b3"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03854naa a2200433 4500 | |
| 001 | oai:lup.lub.lu.se:6e061dc0-17a5-4a8e-b176-2731b26027b3 | |
| 003 | SwePub | |
| 008 | 221109s2022 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/6e061dc0-17a5-4a8e-b176-2731b26027b32 URI |
| 024 | 7 | a https://doi.org/10.1016/j.joca.2022.08.0012 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Johansson, M. S.u University of Southern Denmark4 aut |
| 245 | 1 0 | a Chronic opioid use before and after exercise therapy and patient education among patients with knee or hip osteoarthritis |
| 264 | 1 | b Elsevier BV,c 2022 |
| 300 | a 9 s. | |
| 520 | a Objective: To investigate changes in opioid use after supervised exercise therapy and patient education among knee or hip osteoarthritis patients with chronic opioid use. Method: In this cohort study, we linked data from the Good Life with osteoArthritis in Denmark register (GLA:D®; standardised treatment program for osteoarthritis; January 2013 to November 2018) with national health registries. Among 35,549 patients, 1,262 were classified as chronic opioid users based on amount and temporal distribution of dispensed opioids the year before the intervention. We investigated changes in opioid use, measured as mg oral morphine equivalents (OMEQs), from the year before the intervention to the year after using generalized estimating equations. Results: We found a 10% decrease in mg OMEQs from the year before to the year after the intervention (incidence rate ratio [IRR]: 0.90, 95% confidence interval [CI]: 0.86, 0.94). Additional analyses suggested this decrease to be mainly attributable to regulatory actions targeting opioid prescribing during the study period (IRR among patients participating in the intervention before: 0.98 [95% CI: 0.89, 1.07] vs after: 0.83 [0.74, 0.93] regulatory actions). In a random general population sample of matched chronic opioid users, a similar opioid use pattern was observed over time, further supporting the impact of regulatory actions on the opioid use in the study population. Conclusion: Among patients with knee or hip osteoarthritis and chronic opioid use, a standardised treatment program did not change opioid use when regulatory changes in opioid prescribing were taken into account. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng |
| 653 | a Chronic opioid use | |
| 653 | a Deprescribing | |
| 653 | a Exercise therapy | |
| 653 | a Osteoarthritis | |
| 653 | a Patient education | |
| 700 | 1 | a Pottegård, A.u University of Southern Denmark4 aut |
| 700 | 1 | a Søndergaard, J.u University of Southern Denmark4 aut |
| 700 | 1 | a Englund, M.u Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-med |
| 700 | 1 | a Grønne, D. T.u University of Southern Denmark4 aut |
| 700 | 1 | a Skou, S. T.u University of Southern Denmark4 aut |
| 700 | 1 | a Roos, E. M.u University of Southern Denmark4 aut0 (Swepub:lu)ort-ero |
| 700 | 1 | a Thorlund, J. B.u University of Southern Denmark4 aut |
| 710 | 2 | a University of Southern Denmarkb Ortopedi, Lund4 org |
| 773 | 0 | t Osteoarthritis and Cartilaged : Elsevier BVg 30:11, s. 1536-1544q 30:11<1536-1544x 1063-4584 |
| 856 | 4 | u http://dx.doi.org/10.1016/j.joca.2022.08.001x freey FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/6e061dc0-17a5-4a8e-b176-2731b26027b3 |
| 856 | 4 8 | u https://doi.org/10.1016/j.joca.2022.08.001 |
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