Sökning: onr:"swepub:oai:lup.lub.lu.se:6ec95ec6-914a-4280-a988-b452d8122c98" > Relevance of biomar...
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000 | 07912naa a2200781 4500 | |
001 | oai:lup.lub.lu.se:6ec95ec6-914a-4280-a988-b452d8122c98 | |
003 | SwePub | |
008 | 200616s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:143795169 | |
009 | oai:gup.ub.gu.se/293357 | |
024 | 7 | a https://lup.lub.lu.se/record/6ec95ec6-914a-4280-a988-b452d8122c982 URI |
024 | 7 | a https://doi.org/10.1186/s13195-020-00601-w2 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1437951692 URI |
024 | 7 | a https://gup.ub.gu.se/publication/2933572 URI |
040 | a (SwePub)lud (SwePub)kid (SwePub)gu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a for2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Ehrenberg, Alexander J.u University of California, Berkeley,University of California, San Francisco4 aut |
245 | 1 0 | a Relevance of biomarkers across different neurodegenerative |
264 | c 2020-05-13 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
520 | a Background: The panel of fluid- and imaging-based biomarkers available for neurodegenerative disease research is growing and has the potential to close important gaps in research and the clinic. With this growth and increasing use, appropriate implementation and interpretation are paramount. Various biomarkers feature nuanced differences in strengths, limitations, and biases that must be considered when investigating disease etiology and clinical utility. For example, neuropathological investigations of Alzheimer's disease pathogenesis can fall in disagreement with conclusions reached by biomarker-based investigations. Considering the varied strengths, limitations, and biases of different research methodologies and approaches may help harmonize disciplines within the neurodegenerative disease field. Purpose of review: Along with separate review articles covering fluid and imaging biomarkers in this issue of Alzheimer's Research and Therapy, we present the result of a discussion from the 2019 Biomarkers in Neurodegenerative Diseases course at the University College London. Here, we discuss themes of biomarker use in neurodegenerative disease research, commenting on appropriate use, interpretation, and considerations for implementation across different neurodegenerative diseases. We also draw attention to areas where biomarker use can be combined with other disciplines to understand issues of pathophysiology and etiology underlying dementia. Lastly, we highlight novel modalities that have been proposed in the landscape of neurodegenerative disease research and care. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a Alzheimer's disease | |
653 | a Amyloid | |
653 | a Biomarkers | |
653 | a Cerebrospinal fluid | |
653 | a Magnetic resonance imaging | |
653 | a Neurodegenerative diseases | |
653 | a Neurofilament light chain | |
653 | a Plasma biomarkers | |
653 | a Positron emission tomography | |
653 | a Tau | |
700 | 1 | a Khatun, Ayeshau University College London4 aut |
700 | 1 | a Coomans, Emmau Amsterdam UMC - Vrije Universiteit Amsterdam4 aut |
700 | 1 | a Betts, Matthew J.u German Center for Neurodegenerative Diseases (DZNE), Bonn,Otto von Guericke University Magdeburg4 aut |
700 | 1 | a Capraro, Federicau Francis Crick Institute4 aut |
700 | 1 | a Thijssen, Elisabeth H.u Amsterdam UMC - Vrije Universiteit Amsterdam,University of California, San Francisco4 aut |
700 | 1 | a Senkevich, Konstantinu Petersburg Nuclear Physics Institute (PNPI),Pavlov University4 aut |
700 | 1 | a Bharucha, Tehminau University of Oxford4 aut |
700 | 1 | a Jafarpour, Mehrsau University College London4 aut |
700 | 1 | a Young, Peter N.E.u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut |
700 | 1 | a Jagust, Williamu University of California, Berkeley,Lawrence Berkeley National Laboratory4 aut |
700 | 1 | a Carter, Stephen F.u University of Manchester,University of Cambridge4 aut |
700 | 1 | a Lashley, Tammarynu University College London4 aut |
700 | 1 | a Grinberg, Lea T.u University of São Paulo,University of California, San Francisco4 aut |
700 | 1 | a Pereira, Joana B.u Karolinska Institutet,Karolinska Institute,Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups4 aut0 (Swepub:lu)jo7228pe |
700 | 1 | a Mattsson-Carlgren, Niklasu Gothenburg University,Göteborgs universitet,Lund University,Lunds universitet,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine,Sahlgrenska Academy,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:lu)med-nmn |
700 | 1 | a Ashton, Nicholas J.u Gothenburg University,Göteborgs universitet,Wallenberg Centre for Molecular and Translational Medicine,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xashtn |
700 | 1 | a Hanrieder, Jörg,d 1980u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xhanrj |
700 | 1 | a Zetterberg, Henriku Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xzethe |
700 | 1 | a Schöll, Michaelu Gothenburg University,Göteborgs universitet,Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Sahlgrenska Academy,University College London,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Wallenberg Centre for Molecular and Translational Medicine,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xschom |
700 | 1 | a Paterson, Ross W.u University College London4 aut |
710 | 2 | a University of California, Berkeleyb University of California, San Francisco4 org |
773 | 0 | t Alzheimer's Research and Therapyd : Springer Science and Business Media LLCg 12q 12x 1758-9193 |
856 | 4 | u http://dx.doi.org/10.1186/s13195-020-00601-wx freey FULLTEXT |
856 | 4 | u https://alzres.biomedcentral.com/track/pdf/10.1186/s13195-020-00601-w |
856 | 4 8 | u https://lup.lub.lu.se/record/6ec95ec6-914a-4280-a988-b452d8122c98 |
856 | 4 8 | u https://doi.org/10.1186/s13195-020-00601-w |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:143795169 |
856 | 4 8 | u https://gup.ub.gu.se/publication/293357 |
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