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Measuring density a...
Measuring density and compressibility of white blood cells and prostate cancer cells by microchannel acoustophoresis
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- Barnkob, Rune (författare)
- Technical University of Denmark
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- Augustsson, Per (författare)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Acoustofluidics group,Forskargrupper vid Lunds universitet,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Lund University Research Groups
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- Magnusson, Cecilia (författare)
- Skåne University Hospital
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- Lilja, Hans (författare)
- Skåne University Hospital,Memorial Sloan-Kettering Cancer Center
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- Laurell, Thomas (författare)
- Lund University,Lunds universitet,SEBRA Sepsis and Bacterial Resistance Alliance,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Bruus, Henrik (författare)
- Technical University of Denmark
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visa färre...
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(creator_code:org_t)
- 2011
- 2011
- Engelska.
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Ingår i: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. - 9781618395955 ; 1, s. 127-129
- Relaterad länk:
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https://lup.lub.lu.s...
Abstract
Ämnesord
Stäng
- We present a novel method for the determination of density and compressibility of individual particles and cells undergoing microchannel acoustophoresis in an arbitrary 2D acoustic field. Our method is a critical advancement within acoustophoretic separation of biological cells, as the ability to determine the density and compressibility of individual cells enables the prediction and alteration of the separation outcome for a given cell mixture. We apply the method on white blood cells (WBCs) and DU145 prostate cancer cells (DUCs) aiming to improve isolation of circulating tumor cells from blood, an emerging tool in the monitoring and characterizing of metastatic cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Acoustophoresis
- Cell handling
- Micro-PIV
- Ultrasound resonances
Publikations- och innehållstyp
- kon (ämneskategori)
- ref (ämneskategori)
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