Sökning: onr:"swepub:oai:lup.lub.lu.se:7efeefa6-e900-4947-882d-964899c0f21d" > Bioactive compounds...
Fältnamn | Indikatorer | Metadata |
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000 | 02903naa a2200409 4500 | |
001 | oai:lup.lub.lu.se:7efeefa6-e900-4947-882d-964899c0f21d | |
003 | SwePub | |
008 | 160401s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/79756142 URI |
024 | 7 | a https://doi.org/10.1515/znc-2015-50052 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Aqueveque, Pedro4 aut |
245 | 1 0 | a Bioactive compounds isolated from submerged fermentations of the Chilean fungus Stereum rameale |
264 | c 2015-05-28 | |
264 | 1 | b Walter de Gruyter GmbH,c 2015 |
520 | a Liquid fermentations of the fungus Stereum rameale (No 2511) yielded extracts with antibacterial -activity. The antibacterial activity reached its peak after 216 h of stirring. Bioassay-guided fractionation methods were employed for the isolation of the bioactive metabolites. Three known compounds were identified: MS-3 (1), vibralactone (2) and vibralactone B (3). The three compounds showed antibacterial activity as a function of their concentration. Minimal bactericidal concentrations (MBC) of compound 1 against Gram-positive bacteria were as follows: Bacillus cereus (50 mu g/mL), Bacillus subtilis (10 mu g/mL) and Staphylococcus aureus (100 mu g/mL). Compounds 2 and 3 were active only against Gram-negative bacteria. The MBC of compound 2 against Escherichia coli was 200 mu g/mL. Compound 3 inhibited significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 mu g/mL, respectively. | |
650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
653 | a antibacterial activity | |
653 | a MIC | |
653 | a MS-3 | |
653 | a Stereum rameale | |
653 | a vibralactone | |
700 | 1 | a Leonardo Cespedes, Carlos4 aut |
700 | 1 | a Becerra, Jose4 aut |
700 | 1 | a Davila, Marcelo4 aut |
700 | 1 | a Sterner, Olovu Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)ok2-ost |
710 | 2 | a Centrum för analys och syntesb Kemiska institutionen4 org |
773 | 0 | t Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciencesd : Walter de Gruyter GmbHg 70:3-4, s. 97-102q 70:3-4<97-102x 0939-5075 |
773 | 0 | t Zeitschrift für Naturforschung Cd : Walter de Gruyter GmbHg 70:3-4, s. 97-102q 70:3-4<97-102x 1865-7125 |
856 | 4 | u http://dx.doi.org/10.1515/znc-2015-5005y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/7975614 |
856 | 4 8 | u https://doi.org/10.1515/znc-2015-5005 |
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