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Sökning: onr:"swepub:oai:lup.lub.lu.se:8fd8c4ad-869f-448a-9071-81fa9e948544" > Validation of cause...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005940naa a2200505 4500
001oai:lup.lub.lu.se:8fd8c4ad-869f-448a-9071-81fa9e948544
003SwePub
008221014s2022 | |||||||||||000 ||eng|
009oai:gup.ub.gu.se/317277
0247 a https://lup.lub.lu.se/record/8fd8c4ad-869f-448a-9071-81fa9e9485442 URI
0247 a https://doi.org/10.1111/ctr.147562 DOI
0247 a https://gup.ub.gu.se/publication/3172772 URI
040 a (SwePub)lud (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Gjesdal, Grundeu Lund University,Lunds universitet,Heart Failure and Mechanical Support,Forskargrupper vid Lunds universitet,Molecular Epidemiology and Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)gr5546gj
2451 0a Validation of cause of death classification after heart transplantation and cause-specific life expectancy compared to the general population
264 c 2022-06-28
264 1b Wiley,c 2022
520 a Background: Post heart-transplant survival has increased, but information is lacking on specific causes of death and life expectancy. We aimed to assess cause-specific loss of life-years compared to the general population, evaluate classification for cause of death after heart transplantation, and assess validity of cause of death data from the International Society of Heart and Lung Transplant (ISHLT) registry. Methods: In this single center study, we included 239 heart recipients transplanted between 1988 and 2019 in Lund, Sweden (n = 239, 50% of the transplanted population where the cause of death was available). Two cardiologists retrospectively assigned causes of death according to a published classification (CLASS) in the 91 recipients who died during follow-up. Life expectancy was compared to data from the general population. Results: Compared to the average Swedish population, life expectancy for heart transplant recipients was 20 years shorter (IQR 12.9–27.2). The largest number of life-years lost were for deaths due to acute (49 years) and chronic rejection (27 years). Primary graft dysfunction (24 years) accounted for 24% of deaths, followed by malignancy (20 years) and infection (17 years), each accounting for ∼20% of deaths. Use of CLASS revealed moderate inter-rater agreement (56%) and moderate agreement with the ISHLT registry (62%). Conclusions: Survival after heart transplantation was 20 years lower than in the general population. In the young, more life-years were lost due to acute graft rejection, whereas chronic graft rejection and primary graft failure were more important causes of death in older patients. Agreement was moderate between CLASS and the ISHLT registry classifications.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a cause of death
653 a heart transplant
653 a ISHLT register
653 a life-years-lost
653 a Scandiatransplant
653 a validation
653 a Scandiatransplant; cause of death
653 a life-years-lost; validation
7001 a Lundgren, Jakobu Lund University,Lunds universitet,Lund Hemodynamic Lab,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-jle
7001 a Czuba, Tomaszu Gothenburg University,Göteborgs universitet,University of Gothenburg,Lund University,Lunds universitet,Molecular Epidemiology and Cardiology,Forskargrupper vid Lunds universitet,Lund University Research Groups,Sahlgrenska University Hospital, Wallenberg Laboratory,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xczuto
7001 a Wareham, Neval Eteu Copenhagen University Hospital4 aut
7001 a Gustafsson, Finnu Copenhagen University Hospital4 aut
7001 a Nilsson, Johanu Lund University,Lunds universitet,Hjärt- och lungtransplantation,Forskargrupper vid Lunds universitet,Artificiell intelligens och bioinformatik inom thoraxkirurgisk vetenskap,Heart and Lung transplantation,Lund University Research Groups,Artificial Intelligence and Bioinformatics in Cardiothoracic Sciences (AIBCTS),Skåne University Hospital4 aut0 (Swepub:lu)thor-jni
7001 a Smith, J. Gustavu Gothenburg University,Göteborgs universitet,University of Gothenburg,Lund University,Lunds universitet,Heart Failure and Mechanical Support,Forskargrupper vid Lunds universitet,Molecular Epidemiology and Cardiology,Cardiovascular Epigenetics,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,Lund University Research Groups,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine,Sahlgrenska University Hospital,Sahlgrenska University Hospital, Wallenberg Laboratory,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xsmigu
7001 a Braun, Oscaru Lund University,Lunds universitet,Heart Failure and Mechanical Support,Forskargrupper vid Lunds universitet,Molecular Epidemiology and Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kard-oos
7102 a Heart Failure and Mechanical Supportb Forskargrupper vid Lunds universitet4 org
7730 t Clinical Transplantationd : Wileyg 36:9q 36:9x 0902-0063x 1399-0012
8564 u http://dx.doi.org/10.1111/ctr.14756x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/8fd8c4ad-869f-448a-9071-81fa9e948544
8564 8u https://doi.org/10.1111/ctr.14756
8564 8u https://gup.ub.gu.se/publication/317277

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