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Bio-based starch na...
Bio-based starch nanoparticles with controlled size as antimicrobial agents nanocarriers
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- Morán, Diana (författare)
- University of Oviedo
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- Marefati, Ali (författare)
- Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH
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- Luque, Susana (författare)
- University of Oviedo
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- Schmidt, Marcus (författare)
- Max Rubner-Institut
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- Rayner, Marilyn (författare)
- Oatly AB
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- Blanco-López, María Carmen (författare)
- University of Oviedo
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- Gutiérrez, Gemma (författare)
- University of Oviedo
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- Matos, María (författare)
- University of Oviedo
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: Reactive and Functional Polymers. - 1381-5148. ; 198
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Starch nanoparticles (SNPs) have been synthesized by nanoprecipitation method using starches from different botanical sources in native form and modified with octenyl succinic anhydride (OSA). SNPs were characterized in terms of size, morphology, charge, XRPD, FTIR and thermal properties. Spherical particles were obtained with sizes ranging from 54 to 108 nm and zeta potential values from −2 to −27 mV. Changes in size and stability related to the % OSA were observed for each starch. Starch granules showed A-type crystalline pattern while a loss of crystallinity was observed for SNPs. FTIR spectra demonstrated that OSA modification was barely affected by the nanoprecipitation and SNPs showed thermal properties similar to those of starch granules. SNPs with specific size can be synthesized by selecting the appropriate starch granules as raw material. This is especially relevant in certain bio-applications, where size must be precisely controlled, e.g., as nanocarriers for drug release or food fortification. To investigate the feasibility of SNPs as nanocarriers, vanillin-loaded SNPs were synthesized, achieving encapsulation efficiencies of 30% and loading capacities of 60%. The antimicrobial activity of vanillin-loaded SNPs was tested against Escherichia Coli (E. coli) with satisfactory results.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology (hsv//eng)
Nyckelord
- Absolute ethanol (PubChem CID: 702)
- Antimicrobial
- Controlled size
- methanol (PubChem CID: 887)
- Nanocarriers
- OSA modification
- Starch nanoparticles
- vanillin (PubChem CID: 1183)
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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