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Sökning: onr:"swepub:oai:lup.lub.lu.se:9eadb0d5-3d79-4b0f-ad15-2c217466ec2f" > Validity of continu...

  • Merino, JordiMassachusetts General Hospital,Harvard Medical School,Broad Institute (författare)

Validity of continuous glucose monitoring for categorizing glycemic responses to diet : Implications for use in personalized nutrition

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2022
  • 8 s.

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:9eadb0d5-3d79-4b0f-ad15-2c217466ec2f
  • https://lup.lub.lu.se/record/9eadb0d5-3d79-4b0f-ad15-2c217466ec2fURI
  • https://doi.org/10.1093/ajcn/nqac026DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Background: Continuous glucose monitor (CGM) devices enable characterization of individuals' glycemic variation. However, there are concerns about their reliability for categorizing glycemic responses to foods that would limit their potential application in personalized nutrition recommendations. Objectives: We aimed to evaluate the concordance of 2 simultaneously worn CGM devices in measuring postprandial glycemic responses. Methods: Within ZOE PREDICT (Personalised Responses to Dietary Composition Trial) 1, 394 participants wore 2 CGM devices simultaneously [n = 360 participants with 2 Abbott Freestyle Libre Pro (FSL) devices; n = 34 participants with both FSL and Dexcom G6] for ≤14 d while consuming standardized (n = 4457) and ad libitum (n = 5738) meals. We examined the CV and correlation of the incremental area under the glucose curve at 2 h (glucoseiAUC0-2 h). Within-subject meal ranking was assessed using Kendall τ rank correlation. Concordance between paired devices in time in range according to the American Diabetes Association cutoffs (TIRADA) and glucose variability (glucose CV) was also investigated. Results: The CV of glucoseiAUC0-2 h for standardized meals was 3.7% (IQR: 1.7%-7.1%) for intrabrand device and 12.5% (IQR: 5.1%-24.8%) for interbrand device comparisons. Similar estimates were observed for ad libitum meals, with intrabrand and interbrand device CVs of glucoseiAUC0-2 h of 4.1% (IQR: 1.8%-7.1%) and 16.6% (IQR: 5.5%-30.7%), respectively. Kendall τ rank correlation showed glucoseiAUC0-2h-derived meal rankings were agreeable between paired CGM devices (intrabrand: 0.9; IQR: 0.8-0.9; interbrand: 0.7; IQR: 0.5-0.8). Paired CGMs also showed strong concordance for TIRADA with a intrabrand device CV of 4.8% (IQR: 1.9%-9.8%) and an interbrand device CV of 3.2% (IQR: 1.1%-6.2%). Conclusions: Our data demonstrate strong concordance of CGM devices in monitoring glycemic responses and suggest their potential use in personalized nutrition.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Linenberg, InbarZoe Global Limited (författare)
  • Bermingham, Kate M.King's College London (författare)
  • Ganesh, SajaysuryaZoe Global Limited (författare)
  • Bakker, ElcoZoe Global Limited (författare)
  • Delahanty, Linda M.Massachusetts General Hospital,Harvard Medical School (författare)
  • Chan, Andrew T.Harvard Medical School (författare)
  • Capdevila Pujol, JoanZoe Global Limited (författare)
  • Wolf, JonathanZoe Global Limited (författare)
  • Al Khatib, HayaZoe Global Limited (författare)
  • Franks, Paul W.Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Harvard University,Harvard T.H. Chan School of Public Health(Swepub:lu)med-plf (författare)
  • Spector, Tim D.King's College London (författare)
  • Ordovas, Jose M.Autonomous University of Madrid,Jean Mayer USDA Human Nutrition Research Center on Aging (författare)
  • Berry, Sarah E.King's College London (författare)
  • Valdes, Ana M.University of Nottingham (författare)
  • Massachusetts General HospitalHarvard Medical School (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:American Journal of Clinical Nutrition: Elsevier BV115:6, s. 1569-15760002-9165

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