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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005261naa a2200781 4500
001oai:lup.lub.lu.se:9f4405a3-f31e-4c66-90ec-5097a5d8cd54
003SwePub
008160401s2012 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-64048
0247 a https://lup.lub.lu.se/record/33678852 URI
0247 a https://doi.org/10.1158/1055-9965.EPI-12-08352 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-640482 URI
040 a (SwePub)lud (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Steffen, Annika4 aut
2451 0a Meat and Heme Iron Intake and Risk of Squamous Cell Carcinoma of the Upper Aero-Digestive Tract in the European Prospective Investigation into Cancer and Nutrition (EPIC)
264 1c 2012
520 a Background: Evidence from prospective studies on intake of meat and fish and risk of squamous cell carcinoma (SCC) of the upper aero-digestive tract (UADT) is scarce. We prospectively investigated the association of meat and fish intake with risk of SCC of the UADT and the possible mechanism via heme iron in the large multicenter European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Multivariable proportional hazards models were used to estimate relative risks (RR) of SCC of the UADT in relation to intake of total meat, as well as subtypes of meat, fish, and heme iron among 348,738 individuals from 7 European countries. Results: During an average follow-up of 11.8 years, a total of 682 incident cases of UADT SCC were accrued. Intake of processed meat was positively associated with risk of SCC of the UADT in the total cohort (highest vs. lowest quintile: RR = 1.41; 95% confidence interval (CI) = 1.03-1.941, however, in stratified analyses, this association was confined to the group of current smokers (highest vs. lowest quintile: RR = 1.89; 95% CI = 1.22-2.93). Red meat, poultry, fish, and heme iron were not consistently related to UADT SCC. Conclusion: Higher intake of processed meat was positively associated with KC of the UADT among smokers. Although this finding was stable in various sensitivity analyses, we cannot rule out residual confounding by smoking. Confirmation in future studies and identification of biologic mechanisms is warranted. Impact: Smokers may further increase their risk for SCC of the UADT if they additionally consume large amounts of processed meat. Cancer Epidemiol Biomarkers Prev; 21(12); 2738-48. (C)2012 AACR.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
7001 a Bergmann, Manuela M.4 aut
7001 a Sanchez, Maria-Jose4 aut
7001 a Chirlaque, Maria-Dolores4 aut
7001 a Jakszyn, Paula4 aut
7001 a Amiano, Pilar4 aut
7001 a Ramon Quiros, J.4 aut
7001 a Barricarte Gurrea, Aurelio4 aut
7001 a Ferrari, Pietro4 aut
7001 a Romieu, Isabelle4 aut
7001 a Fedirko, Veronika4 aut
7001 a Bueno-de-Mesquita, H. B(as)4 aut
7001 a Siersema, Peter D.4 aut
7001 a Peeters, Petra H. M.4 aut
7001 a Khaw, Kay-Tee4 aut
7001 a Wareham, Nick4 aut
7001 a Allen, Naomi E.4 aut
7001 a Crowe, Francesca L.4 aut
7001 a Skeie, Guri4 aut
7001 a Hallmanns, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001
7001 a Johansson, Ingegerdu Umeå universitet,Institutionen för odontologi4 aut0 (Swepub:umu)injo0003
7001 a Borgquist, Signeu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ront-sbo
7001 a Ericson, Ulrikau Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)medf-upe
7001 a Egeberg, Rikke4 aut
7001 a Tjonneland, Anne4 aut
7001 a Overvad, Kim4 aut
7001 a Grote, Verena4 aut
7001 a Li, Kuanrong4 aut
7001 a Trichopoulou, Antonia4 aut
7001 a Oikonomidou, Despoina4 aut
7001 a Pantzalis, Menelaos4 aut
7001 a Tumino, Rosario4 aut
7001 a Panico, Salvatore4 aut
7001 a Palli, Domenico4 aut
7001 a Krogh, Vittorio4 aut
7001 a Naccarati, Alessio4 aut
7001 a Mouw, Traci4 aut
7001 a Vergnaud, Anne-Claire4 aut
7001 a Norat, Teresa4 aut
7001 a Boeing, Heiner4 aut
7102 a Umeå universitetb Näringsforskning4 org
7730 t Cancer Epidemiology Biomarkers & Preventiong 21:12, s. 2138-2148q 21:12<2138-2148x 1538-7755x 1055-9965
8564 u http://dx.doi.org/10.1158/1055-9965.EPI-12-0835y FULLTEXT
8564 8u https://lup.lub.lu.se/record/3367885
8564 8u https://doi.org/10.1158/1055-9965.EPI-12-0835
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-64048

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