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Conjugated linoleic...
Conjugated linoleic acid increased C-reactive protein in human subjects
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- Smedman, A (författare)
- Uppsala universitet,Enheten för klinisk näringsforskning
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- Basu, S (författare)
- Uppsala universitet,Enheten för klinisk näringsforskning
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- Jovinge, Stefan (författare)
- Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine
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- Nordin Fredrikson, Gunilla (författare)
- Malmö högskola,Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups,Fakulteten för hälsa och samhälle (HS)
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- Vessby, B (författare)
- Uppsala universitet,Enheten för klinisk näringsforskning
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(creator_code:org_t)
- Published on behalf of the Nutrition Society by CABI Publishing, 2005
- 2005
- Engelska.
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Ingår i: British Journal of Nutrition. - : Published on behalf of the Nutrition Society by CABI Publishing. - 1475-2662 .- 0007-1145. ; 94:5, s. 791-795
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- We previously showed that conjugated linoleic acid (CLA) increases 15-keto-dihydro-prostaglandin F-2 alpha, a marker for cyclooxygenase-mediated lipid peroxidation and thus an indicator of cyclooxygenase-mediated inflammation. The aim of the present study was to investigate the effects of CLA on other indicators of inflammation in human subjects, including C-reactive protein, TNF-alpha, TNF-alpha receptors 1 and 2, and vascular cell adhesion molecule-1. In a double-blind, placebo-controlled study, fifty-three human subjects were supplemented with a mixture (4.2 g/d) of the isomers cis-9,trans-11 CLA and trans-10,cis-12 CLA or control oil for 3 months. CLA supplementation increased levels of C-reactive protein (P=0.003) compared with the control group. However, no changes in TNF-alpha, TNF-alpha receptors 1 and 2, and vascular cell adhesion molecule-1 were detected.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Nyckelord
- tumour necrosis
- conjugated linoleic acid
- C-reactive protein
- inflammation
- factor-alpha
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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