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Sökning: onr:"swepub:oai:lup.lub.lu.se:b0be8c33-2889-486b-b87d-2d49844c4146" > International Socie...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004893naa a2200517 4500
001oai:lup.lub.lu.se:b0be8c33-2889-486b-b87d-2d49844c4146
003SwePub
008210408s2022 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/b0be8c33-2889-486b-b87d-2d49844c41462 URI
0247 a https://doi.org/10.1016/j.euf.2021.03.0172 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a for2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a van der Kwast, Theou Princess Margaret Hospital University of Toronto4 aut
2451 0a International Society of Urological Pathology Expert Opinion on Grading of Urothelial Carcinoma
264 1b Elsevier BV,c 2022
520 a Context: Grading is the mainstay for treatment decisions for patients with non–muscle-invasive bladder cancer (NMIBC). Objective: To determine the requirements for an optimal grading system for NMIBC via expert opinion. Evidence acquisition: A multidisciplinary working group established by the International Society of Urological Pathology reviewed available clinical, histopathological, and molecular evidence for an optimal grading system for bladder cancer. Evidence synthesis: Bladder cancer grading is a continuum and five different grading systems based on historical grounds could be envisaged. Splitting of the World Health Organization (WHO) 2004 low-grade class for NMIBC lacks diagnostic reproducibility and molecular-genetic support, while showing little difference in progression rate. Subdividing the clinically heterogeneous WHO 2004 high-grade class for NMIBC into intermediate and high risk categories using the WHO 1973 grading is supported by both clinical and molecular-genetic findings. Grading criteria for the WHO 1973 scheme were detailed on the basis of literature findings and expert opinion. Conclusions: Splitting of the WHO 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended. Provision of more detailed histological criteria for the WHO 1973 grading might facilitate the general acceptance of a hybrid four-tiered grading system or—as a preferred option—a more reproducible three-tiered system distinguishing low-, intermediate (high)-, and high-grade NMIBC. Patient summary: Improvement of the current systems for grading bladder cancer may result in better informed treatment decisions for patients with bladder cancer. A three-tiered grading system for non–muscle invasive bladder cancer derived by splitting the heterogeneous World Health Organization (WHO) 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended, as this may result in more informed treatment decisions.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
653 a Bladder cancer
653 a Expert opinion
653 a Grading system
653 a Non-muscle invasive bladder cancer
653 a Pathology
653 a WHO 1973
653 a WHO 2004
7001 a Liedberg, Fredriku Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urology - urothelial cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital4 aut0 (Swepub:lu)urok-fli
7001 a Black, Peter C.u University of British Columbia4 aut
7001 a Kamat, Ashishu University of Texas MD Anderson Cancer Center4 aut
7001 a van Rhijn, Bas W.G.u Antoni Van Leeuwenhoek Hospital4 aut
7001 a Algaba, Ferranu Autonomous University of Barcelona4 aut
7001 a Berman, David M.u Queen's University at Kingston4 aut
7001 a Hartmann, Arndtu Friedrich-Alexander University Erlangen-Nürnberg4 aut
7001 a Lopez-Beltran, Antoniou University of Córdoba, Spain4 aut
7001 a Samaratunga, Hemamaliu University of Queensland,Aquesta Uropathology4 aut
7001 a Varma, Muraliu University Hospital of Wales4 aut
7001 a Cheng, Liangu Indiana University4 aut
7102 a Princess Margaret Hospital University of Torontob Urologi - blåscancer, Malmö4 org
7730 t European Urology Focusd : Elsevier BVg 8:2, s. 438-446q 8:2<438-446x 2405-4569
8564 u http://dx.doi.org/10.1016/j.euf.2021.03.017y FULLTEXT
8564 8u https://lup.lub.lu.se/record/b0be8c33-2889-486b-b87d-2d49844c4146
8564 8u https://doi.org/10.1016/j.euf.2021.03.017

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