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Association between...
Association between hypotension during 24 h ambulatory blood pressure monitoring and reflex syncope : the SynABPM 1 study
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- Rivasi, Giulia (författare)
- Careggi University Hospital,University of Florence
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- Groppelli, Antonella (författare)
- San Luca Hospital
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- Brignole, Michele (författare)
- San Luca Hospital
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- Soranna, Davide (författare)
- Istituto Auxologico Italiano
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- Zambon, Antonella (författare)
- Istituto Auxologico Italiano
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- Bilo, Grzegorz (författare)
- San Luca Hospital
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- Pengo, Martino (författare)
- San Luca Hospital
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- Sharad, Bashaaer (författare)
- Lund University,Skåne University Hospital
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- Hamrefors, Viktor (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital
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- Rafanelli, Martina (författare)
- Careggi University Hospital,University of Florence
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- Testa, Giuseppe Dario (författare)
- University of Florence,Careggi University Hospital
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- Rice, Ciara (författare)
- St James's Hospital
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- Kenny, Rose Anne (författare)
- St James's Hospital,Trinity College Dublin
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- Sutton, Richard (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Hammersmith Hospital,Skåne University Hospital
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- Ungar, Andrea (författare)
- Careggi University Hospital,University of Florence
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- Fedorowski, Artur (författare)
- Karolinska Institutet,Karolinska Institute,Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Karolinska University Hospital,Skåne University Hospital
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- Parati, Gianfranco (författare)
- San Luca Hospital
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(creator_code:org_t)
- 2022-06-29
- 2022
- Engelska.
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Ingår i: European Heart Journal. - : Oxford University Press (OUP). - 1522-9645 .- 0195-668X. ; 43:38, s. 3765-3776
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
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- AIMS: Diagnostic criteria for ambulatory blood pressure monitoring (ABPM) in patients with suspected reflex syncope are lacking. The study hypothesis was that patients with reflex syncope have a higher prevalence of systolic blood pressure (SBP) drops on ABPM.METHODS AND RESULTS: ABPM data from reflex syncope patients and controls, matched by average 24 h SBP, age, sex, and hypertension were compared. Patients with constitutional hypotension, orthostatic hypotension, and predominant cardioinhibition during carotid sinus massage or prolonged electrocardiogram monitoring or competing causes of syncope were excluded. Daytime and nighttime SBP drops (<110, 100, 90, 80 mmHg) were assessed. Findings were validated in an independent sample. In the derivation sample, daytime SBP drops were significantly more common in 158 syncope patients than 329 controls. One or more daytime drops <90 mmHg achieved 91% specificity and 32% sensitivity [odds ratio (OR) 4.6, P < 0.001]. Two or more daytime drops <100 mmHg achieved 84% specificity and 40% sensitivity (OR 3.5, P = 0.001). Results were confirmed in the validation sample of 164 syncope patients and 164 controls: one or more daytime SBP drops <90 mmHg achieved 94% specificity and 29% sensitivity (OR 6.2, P < 0.001), while two or more daytime SBP drops <100 mmHg achieved 83% specificity and 35% sensitivity (OR 2.6, P < 0.001).CONCLUSION: SBP drops during ABPM are more common in reflex syncope patients than in controls. Cut-off values that may be applied in clinical practice are defined. This study expands the current indications for ABPM to patients with reflex syncope.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Rivasi, Giulia
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Groppelli, Anton ...
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Brignole, Michel ...
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Soranna, Davide
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Zambon, Antonell ...
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Bilo, Grzegorz
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visa fler...
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Pengo, Martino
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Sharad, Bashaaer
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Hamrefors, Vikto ...
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Rafanelli, Marti ...
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Testa, Giuseppe ...
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Rice, Ciara
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Kenny, Rose Anne
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Sutton, Richard
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Ungar, Andrea
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Fedorowski, Artu ...
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Parati, Gianfran ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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European Heart J ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet