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Autofluorescence im...
Autofluorescence imaging videoendoscopy in the diagnosis of chronic atrophic fundal gastritis
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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2009-10-30
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Springer Science and Business Media LLC,2010
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:b3cea1e8-26a1-4be2-addc-9200da71f5f1
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https://lup.lub.lu.se/record/1542396URI
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https://doi.org/10.1007/s00535-009-0150-7DOI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Purpose: Diagnosis of chronic atrophic fundal gastritis (CAFG) is important to understand the pathogenesis of gastric diseases and assess the risk of gastric cancer. Autofluorescence imaging videoendoscopy (AFI) may enable the detection of mucosal features not apparent by conventional white-light endoscopy. The purpose of this study was to estimate the diagnostic ability of AFI in CAFG. Methods: A total of 77 patients were enrolled. Images of the gastric body in AFI and white-light mode were taken to assess the extent of gastritis, and biopsies were taken from green (n = 119) and purple (n = 146) mucosa in AFI images. The diagnostic accuracy of green mucosa for CAFG was investigated according to the Sydney system. Results: In per-patient analysis, the accuracy of green mucosa in patients with activity, inflammation, atrophy and intestinal metaplasia was 64, 93, 88 and 81%, respectively. In per-biopsy analysis, the accuracy for activity, inflammation, atrophy and intestinal metaplasia was 55, 62, 76 and 76%, respectively. Green areas in the gastric body exhibited more inflammation (p\0.001), atrophy (p\0.001) and intestinal metaplasia (p\0.001), whereas purple areas rarely contained atrophy or intestinal metaplasia. The kappa statistics for inter- and intra-observer agreement of AFI on assessing the extent of CAFG were 0.66 and 0.47, while those for white-light endoscopy were 0.56 and 0.39. Conclusions: AFI could diagnose the extent of CAFG as a green area in the gastric body, with higher reproducibility compared with white-light endoscopy. Therefore, AFI may be a useful adjunct to endoscopy to identify patients at high risk of developing gastric cancer.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Uedo, N
(författare)
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Ishihara, R
(författare)
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Kawaguchi, T
(författare)
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Kawada, N
(författare)
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Chatani, R
(författare)
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Kizu, T
(författare)
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Tamai, C
(författare)
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Takeuchi, J
(författare)
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Higashino, K
(författare)
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Iishi, H
(författare)
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Tatsuta, M
(författare)
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Tomita, Y
(författare)
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Toth, ErvinLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine(Swepub:lu)ront-eto
(författare)
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Institutionen för kliniska vetenskaper, MalmöMedicinska fakulteten
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Gastroenterology: Springer Science and Business Media LLC45:1, s. 45-510944-11741435-5922
Internetlänk
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Till lärosätets databas
- Av författaren/redakt...
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Inoue T, T
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Uedo, N
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Ishihara, R
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Kawaguchi, T
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Kawada, N
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Chatani, R
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visa fler...
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Kizu, T
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Tamai, C
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Takeuchi, J
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Higashino, K
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Iishi, H
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Tatsuta, M
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Tomita, Y
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Toth, Ervin
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
- Artiklar i publikationen
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Journal of Gastr ...
- Av lärosätet
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Lunds universitet