Decrease in all-cause 30-day mortality after bacteraemia over a 15-year period : A population-based cohort study in Denmark in 2000–2014

Jansåker, Filip (författare): Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Copenhagen University Hospital

Gradel, Kim Oren (författare): University of Southern Denmark,Odense University Hospital

Nielsen, Rikke Thoft (författare): Danish Serum Institute, Copenhagen,Hvidovre Hospital

Schønheyder, Henrik Carl (författare): Aalborg University Hospital,Aalborg University

(creator_code:org_t)

2021-06-02
2021
Engelska.
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1661-7827 .- 1660-4601. ; 18:11

Relaterad länk:: http://dx.doi.org/10... (free); visa fler...; https://www.mdpi.com...; https://lup.lub.lu.s...; https://doi.org/10.3...; visa färre...

Abstract Ämnesord

Stäng

Introduction: Bacteraemia is a frequent infectious condition that strongly affects morbidity and mortality. The incidence is increasing worldwide. This study explores all-cause 30-day mortality after bacteraemia in two out of Denmark’s five healthcare regions with approximately 2.4 million inhabitants. Methods: Clinically significant bacteraemia episodes (n = 55,257) were identified from a geographically well-defined background population between 2000 and 2014, drawing on population-based data regarding bacterial species and vital status. All-cause 30-day mortality was assessed in relation to bacteraemia episodes, number of patients with analysed blood cultures and the background population. Results: We observed a decreasing trend of all-cause 30-day mortality between 2000 and 2014, both in relation to the number of bacteraemia episodes and the background population. Mortality decreased from 22.7% of the bacteraemia episodes in 2000 to 17.4% in 2014 (annual IRR [95% CI]: 0.983 [0.979–0.987]). In relation to the background population, there were 41 deaths per 100,000 inhabitants in 2000, decreasing to 39 in 2014 (annual IRR [95% CI]: 0.988 [0.982–0.993]). Numbers of inhabitants, bacteraemia episodes, and analysed persons having BCs increased during the period. Conclusions: All-cause 30-day mortality in patients with bacteraemia decreased significantly over a 15-year period.

Av författaren/redakt...: Holm, Mona Katri ...; Jansåker, Filip; Gradel, Kim Oren; Nielsen, Rikke T ...; Østergaard Ander ...; Jarløv, Jens Ott ...; visa fler...; Schønheyder, Hen ...; Knudsen, Jenny D ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Infektionsmedici ...

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